Health AI Central
Peer-Reviewed Publication
Eur Radiol2025;35(3):1178-1189.March 1, 2025Journal Article

SPINEPS-automatic whole spine segmentation of T2-weighted MR images using a two-phase approach to multi-class semantic and instance segmentation.

Hendrik Möller1,2, Robert Graf3,4, Joachim Schmitt3, Benjamin Keinert3, Hanna Schön3,5, Matan Atad3,4, Anjany Sekuboyina3,6, Felix Streckenbach5, Florian Kofler3,4,7,8, Thomas Kroencke9,10, Stefanie Bette9, Stefan N Willich11, Thomas Keil11,12,13, Thoralf Niendorf14, Tobias Pischon15,16,17, Beate Endemann14, Bjoern Menze6, Daniel Rueckert4,18, Jan S Kirschke3
1Department of Diagnostic and Interventional Neuroradiology, School of Medicine and Health, Technical University of Munich, Munich, Germany. hendrik.moeller@tum.de.
2Institut Für KI Und Informatik in Der Medizin, Klinikum Rechts Der Isar, Technical University of Munich, Munich, Germany. hendrik.moeller@tum.de.
3Department of Diagnostic and Interventional Neuroradiology, School of Medicine and Health, Technical University of Munich, Munich, Germany.
4Institut Für KI Und Informatik in Der Medizin, Klinikum Rechts Der Isar, Technical University of Munich, Munich, Germany.
5Department of Diagnostic and Interventional Radiology, Pediatric Radiology and Neuroradiology, University Medical Center Rostock, Rostock, Germany.
6Department of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland.
7Helmholtz AI, Helmholtz Munich, Neuherberg, Germany.
8TranslaTUM-Central Institute for Translational Cancer Research, Technical University of Munich, Munich, Germany.
9Department of Diagnostic and Interventional Radiology, University Hospital Augsburg, Augsburg, Germany.
10Centre for Advanced Analytics and Predictive Sciences, Augsburg University, Augsburg, Germany.
11Institute of Social Medicine, Epidemiology and Health Economics, Charité-Universitätsmedizin Berlin, Berlin, Germany.
12Institute of Clinical Epidemiology and Biometry, University of Würzburg, Würzburg, Germany.
13State Institute of Health I, Bavarian Health and Food Safety Auhtority, Erlangen, Germany.
14Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.
15Molecular Epidemiology Research Group, Max-Delbrueck-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany.
16Biobank Technology Platform, Max-Delbrueck-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany.
17Charité-Universitätsmedizin Berlin, Corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
18Department of Computing, Imperial College London, London, UK.
PubMed PMC DOI PDF

Abstract

OBJECTIVES: Introducing SPINEPS, a deep learning method for semantic and instance segmentation of 14 spinal structures (ten vertebra substructures, intervertebral discs, spinal cord, spinal canal, and sacrum) in whole-body sagittal T2-weighted turbo spin echo images. MATERIAL AND METHODS: This local ethics committee-approved study utilized a public dataset (train/test 179/39 subjects, 137 female)…

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