Peer-Reviewed Publication
Neuropsychopharmacology2024;50(2):472-479.December 1, 2024Journal Article
A digital intervention for cognitive deficits following COVID-19: a randomized clinical trial.
Lindsay W Victoria1,2, Lauren E Oberlin1,2,3, Irena P Ilieva1, Abhishek Jaywant1,4, Dora Kanellopoulos1,2, Catherine Mercaldi5, Caitlin A Stamatis5, Deborah N Farlow5, Scott H Kollins5, Ochuwa Tisor1,2, Sama Joshi1,2, Raura Doreste-Mendez1,2, Roy H Perlis6, Faith M Gunning7,8
1Department of Psychiatry, Weill Cornell Medicine, New York, NY, USA.
2Weill Cornell Institute of Geriatric Psychiatry, Weill Cornell Medicine, White Plains, NY, USA.
3Department of Neuroscience, AdventHealth Research Institute, Orlando, FL, USA.
4Department of Rehabilitation Medicine, Weill Cornell Medicine/NewYork-Presbyterian Hospital, New York, NY, USA.
5Akili Interactive Labs, Boston, MA, USA.
6Center for Quantitative Health and Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
7Department of Psychiatry, Weill Cornell Medicine, New York, NY, USA. fgd2002@med.cornell.edu.
8Weill Cornell Institute of Geriatric Psychiatry, Weill Cornell Medicine, White Plains, NY, USA. fgd2002@med.cornell.edu.
Abstract
Post-COVID-19 cognitive deficits are common, persistent, and disabling. Evidence on effective treatments is limited. The goal of this study was to investigate the efficacy of a digital intervention to reduce cognitive and functional deficits in adults with persistent post-COVID-19 cognitive dysfunction. We used the remotely-delivered intervention in a randomized clinical trial conducted from July…
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