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Peer-Reviewed Publication
Radiother Oncol2024;200110500.November 1, 2024Journal Article

Deep learning-assisted interactive contouring of lung cancer: Impact on contouring time and consistency.

Michael J Trimpl1, Sorcha Campbell2, Niki Panakis3, Daniel Ajzensztejn4, Emma Burke5, Shawn Ellis6, Philippa Johnstone7, Emma Doyle8, Rebecca Towers9, Geoffrey Higgins10, Claire Bernard11, Roland Hustinx12, Katherine A Vallis13, Eleanor P J Stride14, Mark J Gooding15
1Institute of Biomedical Engineering, Department of Engineering Science, University of Oxford, Oxford, UK; Department of Oncology, University of Oxford, Oxford, UK; Mirada Medical Ltd, Oxford, UK. Electronic address: michael.trimpl@wadham.ox.ac.uk.
2Edinburgh Cancer Centre, Western General Hospital, Edinburgh, UK. Electronic address: sorcha.campbell@nhslothian.scot.nhs.uk.
3Oxford University Hospitals NHS Foundation Trust, UK. Electronic address: niki.panakis@ouh.nhs.uk.
4Oxford University Hospitals NHS Foundation Trust, UK. Electronic address: daniel.ajzensztejn@ouh.nhs.uk.
5Oxford University Hospitals NHS Foundation Trust, UK. Electronic address: emma.burke1@ouh.nhs.uk.
6Oxford University Hospitals NHS Foundation Trust, UK. Electronic address: shawn.ellis@ouh.nhs.uk.
7Peter MacCallum Cancer Centre, Melbourne, Australia. Electronic address: philippa.johnstone@petermac.org.
8Edinburgh Cancer Centre, Western General Hospital, Edinburgh, UK. Electronic address: emma.doyle@nhs.scot.
9Mirada Medical Ltd, Oxford, UK. Electronic address: rebeccajtowers@yahoo.co.uk.
10Department of Oncology, University of Oxford, Oxford, UK. Electronic address: geoffrey.higgins@oncology.ox.ac.uk.
11Le Centre Hospitalier Universitaire de Liege, BE. Electronic address: c.bernard@chuliege.be.
12Le Centre Hospitalier Universitaire de Liege, BE. Electronic address: rhustinx@uliege.be.
13Department of Oncology, University of Oxford, Oxford, UK. Electronic address: katherine.vallis@oncology.ox.ac.uk.
14Institute of Biomedical Engineering, Department of Engineering Science, University of Oxford, Oxford, UK. Electronic address: eleanor.stride@eng.ox.ac.uk.
15Mirada Medical Ltd, Oxford, UK; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK; Inpictura Ltd, Abingdon, UK. Electronic address: mark.gooding@inpicturamedica.com.

Abstract

BACKGROUND AND PURPOSE: To evaluate the impact of a deep learning (DL)-assisted interactive contouring tool on inter-observer variability and the time taken to complete tumour contouring. MATERIALS AND METHODS: Nine clinicians contoured the gross tumour volume (GTV) using the PET-CT scans of 10 non-small cell lung cancer (NSCLC) patients, either using DL-assisted or manual contouring tools. After…

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