Peer-Reviewed Publication
Eur Radiol2025;35(4):1761-1771.April 1, 2025Journal Article

Generating synthetic high-resolution spinal STIR and T1w images from T2w FSE and low-resolution axial Dixon.

Robert Graf1,2, Paul-Sören Platzek3, Evamaria Olga Riedel3, Su Hwan Kim3, Nicolas Lenhart3, Constanze Ramschütz3, Karolin Johanna Paprottka3, Olivia Ruriko Kertels3, Hendrik Kristian Möller3,4, Matan Atad3,4, Robin Bülow5, Nicole Werner6, Henry Völzke6, Carsten Oliver Schmidt6, Benedikt Wiestler3, Johannes C Paetzold7, Daniel Rueckert4,7, Jan Stefan Kirschke3
1Department of Diagnostic and Interventional Neuroradiology, School of Medicine, Technical University of Munich, Munich, Germany. robert.graf@tum.de.
2Institut für KI und Informatik in der Medizin, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany. robert.graf@tum.de.
3Department of Diagnostic and Interventional Neuroradiology, School of Medicine, Technical University of Munich, Munich, Germany.
4Institut für KI und Informatik in der Medizin, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
5Institute for Diagnostic Radiology and Neuroradiology, University Medicine Greifswald, Greifswald, Germany.
6Institut für Community Medicine, Abteilung SHIP-KEF, University Medicine Greifswald, Greifswald, Germany.
7Professor of Visual Information Processing, Department of Computing, Imperial College London, London, United Kingdom.

Abstract

OBJECTIVES: To generate sagittal T1-weighted fast spin echo (T1w FSE) and short tau inversion recovery (STIR) images from sagittal T2-weighted (T2w) FSE and axial T1w gradient echo Dixon technique (T1w-Dixon) sequences. MATERIALS AND METHODS: This retrospective study used three existing datasets: "Study of Health in Pomerania" (SHIP, 3142 subjects, 1.5 Tesla), "German National Cohort" (NAKO, 2000…

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