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Sci Rep2024;14(1):19946.August 27, 2024Journal Article

Predictors of residual tricuspid regurgitation after interventional therapy: an automated deep-learning CT analysis.

Isabel Mattig1,2,3,4, Elena Romero Dorta1,2, Katherine Fitch5, Alexander Lembcke6, Marc Dewey1,3,4,6,7, Karl Stangl1,2,3, Henryk Dreger8,9,10,11
1Department of Cardiology, Angiology and Intensive Care Medicine, Deutsches Herzzentrum der Charité, Campus Charité Mitte, Berlin, Germany.
2Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, 10117, Berlin, Germany.
3DZHK (German Centre for Cardiovascular Research), Partner Site, Berlin, Germany.
4Berlin Institute of Health at Charité - Universitätsmedizin Berlin, BIH Biomedical Innovation Academy, Berlin, Germany.
5Laralab GmbH, Munich, Germany.
6Department of Radiology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, 10117, Berlin, Germany.
7Berlin University Alliance, BAU, Berlin, Germany.
8Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, 10117, Berlin, Germany. henryk.dreger@dhzc-charite.de.
9DZHK (German Centre for Cardiovascular Research), Partner Site, Berlin, Germany. henryk.dreger@dhzc-charite.de.
10Department of Cardiology, Angiology and Intensive Care Medicine, Deutsches Herzzentrum der Charité, Campus Virchow Klinikum, Augustenburger Platz 1, 13353, Berlin, Germany. henryk.dreger@dhzc-charite.de.
11Structural Heart Intervention Program (SHIP), Deutsches Herzzentrum der Charité, Berlin, Germany. henryk.dreger@dhzc-charite.de.
PubMed PMC DOI PDF

Abstract

Computed tomography (CT) is used as a valuable tool for device selection for interventional therapy in tricuspid regurgitation (TR). We aimed to evaluate predictors of TR reduction using CT and automated deep learning algorithms. Patients with severe to torrential TR and CTs prior to either percutaneous annuloplasty (PA) or tricuspid transcatheter edge-to-edge repair (T-TEER) were enrolled. CTs we…

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