Tackling Non-Small Cell Lung Cancer in Young Adults: From Risk Factors and Genetic Susceptibility to Lung Cancer Profile and Outcomes.

Juan Carlos Laguna^1,2, Marco Tagliamento^3,4, Matteo Lambertini^3,4, James Hiznay⁵, Laura Mezquita^1,2,6

¹Medical Oncology Department, Hospital Clinic of Barcelona, Barcelona, Spain.

²Laboratory of Translational Genomics and Targeted Therapies in Solid Tumors, IDIBAPS, Barcelona, Spain.

³Department of Internal Medicine and Medical Specialties (DIMI), School of Medicine, University of Genova, Genova, Italy.

⁴Department of Medical Oncology, Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genova, Italy.

⁵GenomOncology, Cleveland, OH.

⁶Department of Medicine, University of Barcelona, Barcelona, Spain.

PubMed DOI

Abstract

Lung cancer has traditionally been associated with advanced age; however, its increasing incidence among young adults raises concerning questions regarding its etiology and unique considerations for this population. In contrast to the older population, the onset of lung cancer at younger age may be attributed to a complex interplay of incompletely understood individual susceptibility and prevalent…

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