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Peer-Reviewed Publication
Eur Radiol2024;34(11):7244-7254.November 1, 2024Journal Article

Ultra-low-dose vs. standard-of-care-dose CT of the chest in patients with post-COVID-19 conditions-a prospective intra-patient multi-reader study.

Christian Wassipaul1, Daria Kifjak1,2, Ruxandra-Iulia Milos1, Florian Prayer1,3, Sebastian Roehrich1,4, Melanie Winter1, Lucian Beer1, Martin L Watzenboeck1, Svitlana Pochepnia1, Michael Weber1, Dietmar Tamandl1, Peter Homolka5, Wolfgang Birkfellner5, Helmut Ringl1,6, Helmut Prosch1, Benedikt H Heidinger7
1Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria.
2Department of Radiology, UMass Memorial Medical Center and University of Massachusetts Chan Medical School, Worcester, MA, USA.
3Imaging Verbund, Vienna, Austria.
4contextflow GmbH, Vienna, Austria.
5Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria.
6Department of Diagnostic and Interventional Radiology, Clinic Donaustadt, Vienna Healthcare Group, Vienna, Austria.
7Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria. benedikt.heidinger@meduniwien.ac.at.

Abstract

OBJECTIVES: To conduct an intrapatient comparison of ultra-low-dose computed tomography (ULDCT) and standard-of-care-dose CT (SDCT) of the chest in terms of the diagnostic accuracy of ULDCT and intrareader agreement in patients with post-COVID conditions. METHODS: We prospectively included 153 consecutive patients with post-COVID-19 conditions. All participants received an SDCT and an additional…

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