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Peer-Reviewed Publication
J Orthop Res2024;42(8):1653-1669.August 1, 2024Journal Article

Patellar tendon biomechanical and morphologic properties and their relationship to serum clinical variables in persons with prediabetes and type 2 diabetes.

Shivam H Patel1, Nathan W C Campbell1, Chinonso E Emenim1, Dominick O Farino1, Frederick W Damen2, Joseph V Rispoli2, Craig J Goergen1,2, Jacob M Haus3, Arman Sabbaghi4, Chad C Carroll1
1Department of Health and Kinesiology, Purdue University, West Lafayette, Indiana, USA.
2Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana, USA.
3School of Kinesiology, University of Michigan, Ann Arbor, Michigan, USA.
4Head of Clinical Methods, Unlearn.AI, San Francisco, California, USA.
PubMed PMC DOI PDF

Abstract

Tendon biomechanical properties and fibril organization are altered in patients with diabetes compared to healthy individuals, yet few biomarkers have been associated with in vivo tendon properties. We investigated the relationships between in vivo imaging-based tendon properties, serum variables, and patient characteristics across healthy controls (n = 14, age: 45 ± 5 years, body mass index [BMI]…

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