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Peer-Reviewed Publication
Radiol Cardiothorac Imaging2024;6(1):e230153.February 1, 2024Clinical Trial

Evaluation of Intracardiac Pressures Using Subharmonic-aided Pressure Estimation with Sonazoid Microbubbles.

Cara Esposito1, Priscilla Machado1, Maureen E McDonald1, Michael P Savage1, David Fischman1, Praveen Mehrotra1, Ira S Cohen1, Nicholas Ruggiero1, Paul Walinsky1, Alec Vishnevsky1, Kristopher Dickie1, Marguerite Davis1, Flemming Forsberg1, Jaydev K Dave1
1From the Departments of Radiology (C.E., P.M., F.F., J.K.D.), Medical Imaging and Radiation Sciences (M.E.M.), and Medicine (M.P.S., D.F., P.M., I.S.C., N.R., P.W., A.V., M.D.), Thomas Jefferson University, Philadelphia, Pa; Clarius Mobile Health, Vancouver, Canada (K.D.); and Department of Radiology, Mayo Clinic, Rochester, Minn (J.K.D).

Abstract

Purpose To investigate if the right ventricular (RV) systolic and left ventricular (LV) diastolic pressures can be obtained noninvasively using the subharmonic-aided pressure estimation (SHAPE) technique with Sonazoid microbubbles. Materials and Methods Individuals scheduled for a left and/or right heart catheterization were prospectively enrolled in this institutional review board-approved clinic…

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