Peer-Reviewed Publication
J Med Internet Res2024;26e48467.February 7, 2024Randomized Controlled Trial

Preliminary Efficacy of a Digital Intervention for Adolescent Depression: Randomized Controlled Trial.

Emily Peake1,2, Ian Miller1,3, Jessica Flannery1,4, Lang Chen5, Jessica Lake1,2, Aarthi Padmanabhan1,2
1Limbix Health Inc, San Francisco, CA, United States.
2Big Health Inc, San Francisco, CA, United States.
3Digital Medicine Society, Boston, MA, United States.
4Akili, Boston, MA, United States.
5Neuroscience Unit, Santa Clara University, Santa Clara, CA, United States.

Abstract

BACKGROUND: Adolescent depression is a significant public health concern; however, access to effective mental health care is limited. Digital therapeutics (DTx) can improve access to evidence-based interventions; however, their efficacy in adolescents is sparsely documented. OBJECTIVE: This study aims to examine the efficacy of a mobile app DTx versus an active control as an adjunct treatment for…

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