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Peer-Reviewed Publication
Med Phys2024;51(3):1583-1596.March 1, 2024Journal Article

Development of physiologically-informed computational coronary artery plaques for use in virtual imaging trials.

Thomas J Sauer1, Andrew J Buckler2, Ehsan Abadi1, Melissa Daubert3, Pamela S Douglas3, Ehsan Samei1, William P Segars1
1Center for Virtual Imaging Trials, Carl E. Ravin Advanced Imaging Laboratories, Department of Radiology, the Duke University Medical Center, Durham, North Carolina, USA.
2Elucid Bioimaging, Inc., Boston, Massachusetts, USA.
3Duke Department of Medicine, the Duke University Medical Center, Durham, North Carolina, USA.
PubMed PMC DOI PDF

Abstract

BACKGROUND: As a leading cause of death, worldwide, cardiovascular disease is of great clinical importance. Among cardiovascular diseases, coronary artery disease (CAD) is a key contributor, and it is the attributed cause of death for 10% of all deaths annually. The prevalence of CAD is commensurate with the rise in new medical imaging technologies intended to aid in its diagnosis and treatment. T…

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