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Peer-Reviewed Publication
Alzheimers Res Ther2023;15(1):165.October 4, 2023Journal Article

In vivo cortical diffusion imaging relates to Alzheimer's disease neuropathology.

Mario Torso1, Gerard R Ridgway2, Michele Valotti2, Ian Hardingham2, Steven A Chance2, ,
1Oxford Brain Diagnostics Ltd, Oxford, UK. mario.torso@oxfordbraindiagnostics.com.
2Oxford Brain Diagnostics Ltd, Oxford, UK.
PubMed PMC DOI PDF

Abstract

BACKGROUND: There has been increasing interest in cortical microstructure as a complementary and earlier measure of neurodegeneration than macrostructural atrophy, but few papers have related cortical diffusion imaging to post-mortem neuropathology. This study aimed to characterise the associations between the main Alzheimer's disease (AD) neuropathological hallmarks and multiple cortical microstr…

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