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Peer-Reviewed Publication
Magn Reson Med2024;91(2):541-557.February 1, 2024Journal Article

Eddy current-induced artifact correction in high b-value ex vivo human brain diffusion MRI with dynamic field monitoring.

Gabriel Ramos-Llordén1, Daniel J Park1, John E Kirsch1, Alina Scholz2, Boris Keil2,3, Chiara Maffei1,4, Hong-Hsi Lee1, Berkin Bilgic1, Brian L Edlow1,4, Choukri Mekkaoui1, Anastasia Yendiki1, Thomas Witzel5, Susie Y Huang1,6
1Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, USA.
2Institute of Medical Physics and Radiation Protection, Mittelhessen University of Applied Sciences, Giessen, Germany.
3Department of Diagnostic and Interventional Radiology, University Hospital Marburg, Philipps University of Marburg, Marburg, Germany.
4Center for Neurotechnology and Neurorecovery, Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA.
5Q Bio Inc, San Carlos, California, USA.
6Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.

Abstract

PURPOSE: To investigate whether spatiotemporal magnetic field monitoring can correct pronounced eddy current-induced artifacts incurred by strong diffusion-sensitizing gradients up to 300 mT/m used in high b-value diffusion-weighted (DW) EPI. METHODS: A dynamic field camera equipped with 16 1 H NMR field probes was first used to characterize field perturbations caused by residual eddy currents fr…

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