Peer-Reviewed Publication
Sci Rep2023;13(1):16097.September 26, 2023Observational Study

Use of biomarkers for predicting a malignant course in acute ischemic stroke: an observational case-control study.

Alexandre Guimarães de Almeida Barros1, Lucas Roquim E Silva2, Alberlúcio Pessoa2, Antonio Eiras Falcão3, Luiz Alexandre Viana Magno2, Daniela Valadão Freitas Rosa2, Marco Aurelio Romano Silva2, Debora Marques de Miranda2, Rodrigo Nicolato2
1Medical School of Universidade Federal de Minas Gerais, Prof. Alfredo Balena Avenue, 190, Belo Horizonte, 30130-100, Brazil. xandebarros@gmail.com.
2Medical School of Universidade Federal de Minas Gerais, Prof. Alfredo Balena Avenue, 190, Belo Horizonte, 30130-100, Brazil.
3Medical School of Universidade Estadual de Campinas, R. Vital Brasil, 251, Cidade Universitária, Campinas, 13083-888, Brazil.

Abstract

Acute ischemic stroke is a sudden neurological event caused by brain ischemia. Patients with large vessel occlusion are at high risk of developing significant cerebral edema, which can lead to rapid neurological decline. The optimal timing for decompressive hemicraniectomy to prevent further brain damage is still uncertain. This study aimed to identify potential predictors of severe brain edema. T…

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