Epidemiology, Risk Factors, and Prevention of Head and Neck Squamous Cell Carcinoma.

Adam Barsouk¹, John Sukumar Aluru², Prashanth Rawla³, Kalyan Saginala⁴, Alexander Barsouk⁵

¹Internal Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA.

²Elucid Bioimaging, Boston, MA 02216, USA.

³Parrish Medical Center, Titusville, FL 32796, USA.

⁴Plains Regional Medical Group Internal Medicine, Clovis, NM 88101, USA.

⁵Hematologist-Oncologist, Allegheny Health Network, Pittsburgh, PA 15212, USA.

PubMed PMC DOI PDF

Abstract

Head and neck squamous cell carcinoma (HNSCC) is a group of malignancies, involving the oral cavity, pharynx, hypopharynx, larynx, nasal cavity, and salivary glands, that together compose the seventh most common cancer diagnosis worldwide. With 890,000 new cases and 450,000 deaths annually per GLOBOCAN estimates, HNSCC accounts for roughly 4.5% of cancer diagnoses and deaths. In the developing wor…

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