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Peer-Reviewed Publication
Acta Anaesthesiol Scand2023;67(9):1187-1193.October 1, 2023Journal Article

Generalizability of nociception level as a measure of intraoperative nociceptive stimulation: A retrospective analysis.

Kurt Ruetzler1,2, Mateo Montalvo1, Omer Miller Rotem3, Elyad Ekrami1, Julian Rössler1, Jorge Andres Araujo Duran1, Albert Dahan4, Yaacov Gozal5, Philippe Richebe6, Borzoo Farhang7, Alparslan Turan1,2, Daniel I Sessler1
1Department of Outcomes Research, Anesthesiology Institute, Cleveland Clinic, Cleveland, Ohio, USA.
2Department of General Anesthesiology, Anesthesiology Institute, Cleveland Clinic, Cleveland, Ohio, USA.
3Medasense Biometrics Ltd., Ramat Gan, Israel.
4Department of Anesthesiology, Leiden University Medical Center, Leiden, The Netherlands.
5Department of Anesthesiology, Perioperative Medicine and Pain Treatment, Shaare Medical Center, Jerusalem, Israel.
6Département d'Anesthésiologie et Médecine de la Douleur, Université de Montréal, Montréal, Canada.
7University of Vermont Medical Center, Larner College of Medicine, Department of Anesthesiology, Burlington, Vermont, USA.

Abstract

BACKGROUND: Nociception-guided intraoperative opioid administration might help reduce postoperative pain. A commonly used and validated nociception monitor system is nociception level (NOL), which provides the nociception index, ranging from 0 to 100, with 0 representing no nociception and 100 representing extreme nociception. We tested the hypothesis that NOL responses are similar in men and wome…

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