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Peer-Reviewed Publication
J Clin Sleep Med2023;19(4):769-810.April 1, 2023Systematic Review

Management of REM sleep behavior disorder: an American Academy of Sleep Medicine systematic review, meta-analysis, and GRADE assessment.

Michael Howell1, Alon Y Avidan2, Nancy Foldvary-Schaefer3, Roneil G Malkani4,5, Emmanuel H During6,7, Joshua P Roland8,9, Stuart J McCarter10, Rochelle S Zak11, Gerard Carandang12, Uzma Kazmi12, Kannan Ramar13
1Department of Neurology, University of Minnesota, Minneapolis, Minnesota.
2David Geffen School of Medicine at UCLA, Los Angeles, California.
3Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio.
4Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
5Jesse Brown Veterans Affairs Medical Center, Chicago, Illinois.
6Department of Neurology, Division of Movement Disorders, Icahn School of Medicine at Mount Sinai, New York, New York.
7Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.
8Thirty Madison, New York, New York.
9Department of Pulmonology, Critical Care, and Sleep Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California.
10Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota.
11Sleep Disorders Center, University of California, San Francisco, San Francisco, California.
12American Academy of Sleep Medicine, Darien, Illinois.
13Division of Pulmonary and Critical Care Medicine, Center for Sleep Medicine, Mayo Clinic, Rochester, Minnesota.
PubMed PMC DOI PDF

Abstract

UNLABELLED: This systematic review provides supporting evidence for a clinical practice guideline for the management of rapid eye movement (REM) sleep behavior disorder in adults and children. The American Academy of Sleep Medicine commissioned a task force of 7 experts in sleep medicine. A systematic review was conducted to identify randomized controlled trials and observational studies that addr…

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