Quantitative CT Evaluation of Small Pulmonary Vessels Has Functional and Prognostic Value in Pulmonary Hypertension.

Yousef Shahin¹, Samer Alabed¹, Dheyaa Alkhanfar¹, Juerg Tschirren¹, Alex M K Rothman¹, Robin Condliffe¹, James M Wild¹, David G Kiely¹, Andrew J Swift¹

¹From the Department of Infection, Immunity and Cardiovascular Disease (Y.S., S.A., D.A., A.M.K.R., J.M.W., D.G.K., A.J.S.) and INSIGNEO, Institute for in silico Medicine (D.G.K., A.J.S.), University of Sheffield, Glossop Rd, Sheffield S10 2JF, England; Department of Clinical Radiology, Sheffield Teaching Hospitals, Sheffield, England (Y.S., S.A., A.J.S.); VIDA Diagnostics, Coralville, Iowa (J.T.); and Sheffield Pulmonary Vascular Disease Unit, Royal Hallamshire Hospital, Sheffield, England (R.C., D.G.K.).

PubMed PMC DOI PDF

Abstract

Background The in vivo relationship between peel pulmonary vessels, small pulmonary vessels, and pulmonary hypertension (PH) is not fully understood. Purpose To quantitatively assess peel pulmonary vessel volumes (PPVVs) and small pulmonary vessel volumes (SPVVs) as estimated from CT pulmonary angiography (CTPA) in different subtypes of PH compared with controls, their relationship to pulmonary fu…

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