An expanded reference map of the human gut microbiome reveals hundreds of previously unknown species.

Sigal Leviatan^1,2, Saar Shoer^1,2, Daphna Rothschild^1,2, Maria Gorodetski³, Eran Segal^4,5

¹Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel.

²Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.

³DayTwo LTD, Tel Aviv, Israel.

⁴Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel. eran.segal@weizmann.ac.il.

⁵Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel. eran.segal@weizmann.ac.il.

PubMed PMC DOI PDF

Abstract

The gut is the richest ecosystem of microbes in the human body and has great influence on our health. Despite many efforts, the set of microbes inhabiting this environment is not fully known, limiting our ability to identify microbial content and to research it. In this work, we combine new microbial metagenomic assembled genomes from 51,052 samples, with previously published genomes to produce a…

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