A Real-World Comparative Effectiveness Analysis of Thromboprophylactic Use of Enoxaparin Versus Unfractionated Heparin in Abdominal Surgery Patients in a Large U.S. Hospital Database.

S P Veeranki^1,2,3, Z Xiao⁴, A Levorsen⁵, M Sinha¹, B Shah^6,7

¹Premier Applied Sciences, Premier Inc., Charlotte, NC, USA.

²University of Texas Medical Branch, Galveston, TX, USA.

³Precision HEOR, Los Angeles, CA, USA.

⁴Sanofi, Cambridge, MA, USA.

⁵Sanofi, Oslo, Norway.

⁶Livongo Health, Mountain View, CA, USA.

⁷Duke University, Durham, NC, USA.

PubMed PMC DOI PDF

Abstract

Introduction: Little is known about outcomes associated with enoxaparin versus unfractionated heparin (UFH) for venous thromboembolism (VTE) prophylaxis in abdominal surgery patients in U.S. clinical practice. The purpose of this study was to compare VTE, all-cause mortality, PE-related in-hospital mortality, and hospital costs during abdominal surgery hospitalization and the 90 days post-discharg…

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