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Peer-Reviewed Publication
PLoS One2022;17(5):e0266799.January 1, 2022Journal Article

Validation of a deep learning computer aided system for CT based lung nodule detection, classification, and growth rate estimation in a routine clinical population.

John T Murchison1, Gillian Ritchie1, David Senyszak2, Jeroen H Nijwening3, Gerben van Veenendaal3, Joris Wakkie3, Edwin J R van Beek1,2
1Department of Radiology, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom.
2Edinburgh Imaging facility QMRI, University of Edinburgh, Edinburgh, United Kingdom.
3Aidence, Amsterdam, The Netherlands.

Abstract

OBJECTIVE: In this study, we evaluated a commercially available computer assisted diagnosis system (CAD). The deep learning algorithm of the CAD was trained with a lung cancer screening cohort and developed for detection, classification, quantification, and growth of actionable pulmonary nodules on chest CT scans. Here, we evaluated the CAD in a retrospective cohort of a routine clinical populatio…

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