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Peer-Reviewed Publication
Physiol Rep2022;10(5):e15223.March 1, 2022Journal Article

The answer at our fingertips: Volume status in cirrhosis determined by machine learning and pulse oximeter waveform.

Nikhilesh R Mazumder1,2, Avidor Kazen3, Andrew Carek3, Mozziyar Etemadi4,5, Josh Levitsky6
1Division of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, Michigan, USA.
2Gastroenterology Section, VA Ann Arbor Healthcare System, Ann Arbor, Michigan, USA.
3Cardiosense Inc, Chicago, Illinois, USA.
4McCormick School of Engineering, Northwestern University, Chicago, Illinois, USA.
5Department of Anesthesia, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
6Division of Gastroenterology and Hepatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

Abstract

OBJECTIVE: The objective of our study was to determine if the waveform from a simple pulse oximeter-like device could be used to accurately assess intravascular volume status in cirrhosis. METHODS: Patients with cirrhosis underwent waveform recording as well as serum brain natriuretic peptide (BNP) on the day of their cardiac catheterization where invasive cardiac pressures were measured. Wavefor…

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