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Peer-Reviewed Publication
Rheumatology (Oxford)2022;61(8):3269-3278.August 3, 2022Journal Article

Fully automated opportunistic screening of vertebral fractures and osteoporosis on more than 150 000 routine computed tomography scans.

Christian Roux1, Antoine Rozes2, Daniel Reizine3, David Hajage4, Christel Daniel5,6, Aurélien Maire5, Stéphane Bréant5, Namik Taright7, Ronen Gordon8, Jacques Fechtenbaum9, Sami Kolta9, Antoine Feydy1,10, Karine Briot1, Florence Tubach4
1Department of Rheumatology, INSERM UMR 1153, APHP. Centre-Université de Paris, Institut de Recherche des Maladies Ostéo-Articulaires de l'Université de Paris, Hôpital Cochin.
2AP-HP, Sorbonne Université, Hôpital Pitié Salpêtrière, Centre de Pharmacoépidémiologie (Cephepi), Unité de Recherche Clinique PSL-CFX, CIC-1901.
3AP-HP, Direction des Systèmes d'Information.
4Sorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, AP-HP, Sorbonne Université, Hôpital Pitié Salpêtrière, Département de Santé Publique, Centre de Pharmacoépidémiologie (Cephepi), Unité de Recherche Clinique PSL-CFX, CIC-1901.
5AP-HP, Direction des Systèmes d'Information, Pôle Innovation et Données.
6INSERM UMRS 1142.
7AP-HP, Direction de la Stratégie et de la Transformation, Pôle Sciences des données et Information médicale, Paris, France.
8Zebra Medical Vision Ltd, Shefayim, Israël.
9Department of Rheumatology, APHP, Centre-Université de Paris, Hôpital Cochin.
10Service de Radiologie Ostéo-Articulaire, Hôpital Cochin, Collégiale de Radiologie, AP-HP, Paris, France.
PubMed DOI

Abstract

OBJECTIVE: Osteoporosis is underdiagnosed and undertreated, although severe complications of osteoporotic fractures, including vertebral fractures, are well known. This study sought to assess the feasibility and results of an opportunistic screening of vertebral fractures and osteoporosis in a large database of lumbar or abdominal CT scans. MATERIAL AND METHODS: Data were analysed from CT scans o…

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