Type 2 diabetes reversal with digital twin technology-enabled precision nutrition and staging of reversal: a retrospective cohort study.

Paramesh Shamanna¹, Shashank Joshi², Lisa Shah², Mala Dharmalingam³, Banshi Saboo⁴, Jahangir Mohammed², Maluk Mohamed², Terrence Poon², Nathan Kleinman⁵, Mohamed Thajudeen², Ashok Keshavamurthy²

¹Twin Health, Bangalore, Karnataka, 560043, India.

²Twin Health, Mountain View, California, 94043, USA.

³Bangalore Endocrinology & Diabetes Research Centre, Bangalore, Karnataka, 560003, India.

⁴Diacare - Diabetes Care & Hormone Clinic, Ahmedabad, Gujarat, 380005, India.

⁵Kleinman Analytic Solutions, LLC, Missouri City, TX, 77459, USA. nathan@kleinmansolutions.com.

PubMed PMC DOI PDF

Abstract

BACKGROUND: Type 2 diabetes reversal has been viewed in the literature primarily as a dichotomous event (reversed or not reversed), even though this viewpoint may not be optimal for clinicians or patients. This cohort study's objectives were to define stages of type 2 diabetes reversal and measure changes in reversal stages before and after 90 days of digital twin-enabled precision nutrition thera…

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