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Peer-Reviewed Publication
Heart Rhythm O22021;2(5):511-520.October 1, 2021Journal Article

Computational ECG mapping and respiratory gating to optimize stereotactic ablative radiotherapy workflow for refractory ventricular tachycardia.

Gordon Ho1, Todd F Atwood2, Andrew R Bruggeman2, Kevin L Moore2, Elliot McVeigh3, Christopher T Villongco4, Frederick T Han1, Jonathan C Hsu1, Kurt S Hoffmayer1, Farshad Raissi1, Grace Y Lin5, Amir Schricker6, Christopher E Woods6, Joey P Cheung7, Al V Taira7, Andrew McCulloch3, Ulrika Birgersdotter-Green1, Gregory K Feld1, Arno J Mundt2, David E Krummen1
1Department of Medicine-Cardiology, University of California San Diego, La Jolla, California.
2Department of Radiation Medicine, University of California San Diego, La Jolla, California.
3Department of Bioengineering, University of California San Diego, La Jolla, California.
4Vektor Medical Inc, Carlsbad, California.
5Department of Pathology, University of California San Diego, La Jolla, California.
6Department of Cardiac Electrophysiology, Mills-Peninsula Medical Center, Sutter Health, Burlingame, California.
7Department of Radiation Oncology, Mills-Peninsula Medical Center, Sutter Health, Burlingame, California.

Abstract

BACKGROUND: Stereotactic ablative radiotherapy (SAbR) is an emerging therapy for refractory ventricular tachycardia (VT). However, the current workflow is complicated, and the precision and safety in patients with significant cardiorespiratory motion and VT targets near the stomach may be suboptimal. OBJECTIVE: We hypothesized that automated 12-lead electrocardiogram (ECG) mapping and respiratory…

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