Noninvasive carotid pressure-diameter loops to identify viscoelastic properties in ageing, hypertension and type 2 diabetes.

Alessandro Giudici¹, Carlo Palombo², Michaela Kozakova³, Carmela Morizzo², Giuseppe Penno³, Giuli Jamagidze⁴, Daniele Della Latta^4,5, Dante Chiappino⁴, J Kennedy Cruickshank⁶, Ashraf W Khir¹

¹Brunel Institute for Bioengineering, Brunel University London, Uxbridge, Middlesex, UK.

²Department of Surgical, Medical, Molecular Pathology and Critical Area Medicine.

³Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Tuscany.

⁴G. Pasquinucci Heart Hospital, G. Monasterio Foundation, Massa, Italy.

⁵TeraRecon, Durham, North Carolina, USA.

⁶School of Life-Course/Nutritional Sciences, King's College, St. Thomas' & Guy's Hospitals, London, Middlesex, UK.

PubMed DOI

Abstract

OBJECTIVES: Arterial stiffness as pulse wave velocity (PWV) predicts cardiovascular events independently of blood pressure (BP). PWV does not distinguish between stiffness in systole and diastole. This cross-sectional study aimed to test the hypothesis that viscous and elastic carotid wall properties differ between systole and diastole, distinguishing effects of ageing, hypertension and T2 diabete…

Create a free account to keep reading

Free members get 10 full research views every month across publications, clinical trials, FDA clearances, adverse events, and NIH grants. No credit card required.

Create Free Account Sign In

Want unlimited research access? See Pro plans

Data Accuracy Notice: Research intelligence on Health AI Central is aggregated from public sources (PubMed, ClinicalTrials.gov, FDA, NIH, CMS, and others) and refreshed nightly. Classifications and derived metrics are produced by automated methods described in our Methodology. We recommend verifying critical data points against the primary sources before making decisions.