Health AI Central
Peer-Reviewed Publication
Sci Rep2021;11(1):12252.June 10, 2021Journal Article

Three dimensional reconstruction of coronary artery stents from optical coherence tomography: experimental validation and clinical feasibility.

Wei Wu1, Behram Khan1, Mohammadali Sharzehee1, Shijia Zhao1, Saurabhi Samant1, Yusuke Watanabe2, Yoshinobu Murasato3, Timothy Mickley4, Andrew Bicek4, Richard Bliss5, Thomas Valenzuela6, Paul A Iaizzo6, Janaki Makadia1, Anastasios Panagopoulos1, Francesco Burzotta7, Habib Samady8, Emmanouil S Brilakis9, George D Dangas10, Yves Louvard11, Goran Stankovic12, Gabriele Dubini13, Francesco Migliavacca13, Ghassan S Kassab14, Elazer R Edelman15, Claudio Chiastra16, Yiannis S Chatzizisis17
1Cardiovascular Biology and Biomechanics Laboratory, Cardiovascular Division, University of Nebraska Medical Center, 982265 Nebraska Medical Center, Omaha, NE, 68198, USA.
2Department of Cardiology, Teikyo University Hospital, Tokyo, Japan.
3Department of Cardiology, National Hospital Organization Kyushu Medical Center, Fukuoka, Japan.
4Boston Scientific Inc, Maple Grove, MN, USA.
5Medtronic Inc, Santa Rosa, CA, USA.
6Visible Heart Laboratory, Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN, USA.
7Department of Cardiovascular Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS Università Cattolica del Sacro Cuore, Rome, Italy.
8School of Medicine, Emory University, Atlanta, GA, USA.
9Minneapolis Heart Institute, Minneapolis, MN, USA.
10Department of Cardiovascular Medicine, Mount Sinai Hospital, New York City, NY, USA.
11Institut Cardiovasculaire Paris Sud, Massy, France.
12Department of Cardiology, Clinical Center of Serbia, Belgrade, Serbia.
13Laboratory of Biological Structure Mechanics (LaBS), Department of Chemistry, Materials and Chemical Engineering "Giulio Natta,", Politecnico di Milano, Milan, Italy.
14California Medical Innovation Institute, San Diego, CA, USA.
15Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Boston, MA, USA.
16PoliToBIOMed Lab, Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Turin, Italy.
17Cardiovascular Biology and Biomechanics Laboratory, Cardiovascular Division, University of Nebraska Medical Center, 982265 Nebraska Medical Center, Omaha, NE, 68198, USA. ychatzizisis@icloud.com.
PubMed PMC DOI PDF

Abstract

The structural morphology of coronary stents (e.g. stent expansion, lumen scaffolding, strut apposition, tissue protrusion, side branch jailing, strut fracture), and the local hemodynamic environment after stent deployment are key determinants of procedural success and subsequent clinical outcomes. High-resolution intracoronary imaging has the potential to enable the geometrically accurate three-d…

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