Computational and experimental mechanical performance of a new everolimus-eluting stent purpose-built for left main interventions.

Saurabhi Samant¹, Wei Wu¹, Shijia Zhao¹, Behram Khan¹, Mohammadali Sharzehee¹, Anastasios Panagopoulos¹, Janaki Makadia¹, Timothy Mickley², Andrew Bicek², Dennis Boismier², Yoshinobu Murasato³, Yiannis S Chatzizisis⁴

¹Cardiovascular Biology and Biomechanics Laboratory, Cardiovascular Division, University of Nebraska Medical Center, 982265 Nebraska Medical Center, Omaha, NE, 68198, USA.

²Boston Scientific, Maple Grove, MN, USA.

³Department of Cardiology, National Hospital Organization, Kyushu Medical Center, Fukuoka, Japan.

⁴Cardiovascular Biology and Biomechanics Laboratory, Cardiovascular Division, University of Nebraska Medical Center, 982265 Nebraska Medical Center, Omaha, NE, 68198, USA. ychatzizisis@icloud.com.

PubMed PMC DOI PDF

Abstract

Left main (LM) coronary artery bifurcation stenting is a challenging topic due to the distinct anatomy and wall structure of LM. In this work, we investigated computationally and experimentally the mechanical performance of a novel everolimus-eluting stent (SYNERGY MEGATRON) purpose-built for interventions to large proximal coronary segments, including LM. MEGATRON stent has been purposefully desi…

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