Peer-Reviewed Publication
J Acquir Immune Defic Syndr2021;86(1):73-80.January 1, 2021Journal Article
Randomized Pilot Study of an Advanced Smart-Pill Bottle as an Adherence Intervention in Patients With HIV on Antiretroviral Treatment.
Grant B Ellsworth1, Leah A Burke2, Martin T Wells3, Satish Mishra4, Matthew Caffrey3, David Liddle5, Malika Madhava6, Curtis O'Neal1, Peter L Anderson7, Lane Bushman6, Lucas Ellison6, Josh Stein8, Roy M Gulick1
1Division of Infectious Diseases, Weill Cornell Medicine, New York, NY.
2Yale University School of Medicine, New Haven, CT.
3Cornell University, Ithaca, NY.
4University of Chicago, Chicago, IL.
5Children's National Hospital, Washington DC.
6Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA.
7Department of Pharmaceutical Sciences, University of Colorado Denver, CO; and.
8AdhereTech, New York, NY.
Abstract
BACKGROUND: Adherence is critical to achieve the benefits of antiretroviral therapy. A smart-pill bottle service that transmits real-time adherence data via cellular networks to a central service and prompts nonadherent patients with phone or text messages may improve adherence.
METHODS: Adults with HIV taking a tenofovir-containing regimen with suboptimal adherence were randomized to adherence c…
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