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Peer-Reviewed Publication
Urol Oncol2021;39(2):130.e9-130.e15.February 1, 2021Journal Article

Statin use and risk of prostate cancer biochemical recurrence after radical prostatectomy.

Nicole Prabhu1, Navina Kapur2, William Catalona3, Robin Leikin4, Irene Helenowski5, Borko Jovanovich5, Michael Gurley6, Tochi M Okwuosa7, Timothy M Kuzel8
1Department of Internal Medicine, Rush University Medical Center, Chicago, IL.
2Department of Internal Medicine, Rush University Medical Center, Chicago, IL. Electronic address: navina_c_kapur@rush.edu.
3Department of Urology, Northwestern University, Chicago, IL.
4Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL.
5Department of Preventative Medicine, Northwestern University, Chicago, IL.
6Northwestern University Clinical and Translational Sciences Institute, Chicago, IL.
7Division of Cardiology, Department of Internal Medicine, Rush University Medical Center, Chicago, IL.
8Division of Hematology/Oncology/Cell Therapy, Department of Internal Medicine, Rush University Medical Center, Chicago, IL.

Abstract

BACKGROUND: Multiple studies have investigated the role of statins in prostate cancer (CaP), the leading cause of cancer related death in men. Retrospective cohort studies investigating the correlation between statin use and biochemical recurrence free (BCRF) survival in men with CaP have been inconclusive. OBJECTIVES: In the largest reported surgical cohort to date, we investigated the effect of…

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