Peer-Reviewed Publication
JAMA Neurol2020;78(1):41-7.September 8, 2020Journal Article

Assessment of Brain Injury Using Portable, Low-Field Magnetic Resonance Imaging at the Bedside of Critically Ill Patients.

Kevin N Sheth1, Mercy H Mazurek1, Matthew M Yuen1, Bradley A Cahn1, Jill T Shah1, Adrienne Ward2, Jennifer A Kim1, Emily J Gilmore1, Guido J Falcone1, Nils Petersen1, Kevin T Gobeske1, Firas Kaddouh1, David Y Hwang1, Joseph Schindler1, Lauren Sansing1, Charles Matouk3, Jonathan Rothberg4,5, Gordon Sze6, Jonathan Siner7, Matthew S Rosen8, Serena Spudich9, W Taylor Kimberly10
1Department of Neurology, Yale University School of Medicine, New Haven, Connecticut.
2Neuroscience Intensive Care Unit, Yale New Haven Hospital, New Haven, Connecticut.
3Department of Neurosurgery, Yale School of Medicine, New Haven, Connecticut.
4Department of Genetics, Yale University School of Medicine, New Haven, Connecticut.
5Hyperfine Research Inc, Guilford, Connecticut.
6Department of Radiology, Yale University School of Medicine, New Haven, Connecticut.
7Division of Pulmonology and Sleep Medicine, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut.
8Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown.
9Division of Neurology Infections & Global Neurology, Department of Neurology, Yale University School of Medicine, New Haven, Connecticut.
10Division of Neurocritical Care, Department of Neurology, Massachusetts General Hospital, Boston.

Abstract

IMPORTANCE: Neuroimaging is a key step in the clinical evaluation of brain injury. Conventional magnetic resonance imaging (MRI) systems operate at high-strength magnetic fields (1.5-3 T) that require strict, access-controlled environments. Limited access to timely neuroimaging remains a key structural barrier to effectively monitor the occurrence and progression of neurological injury in intensiv…

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