A Digital Pathology Solution to Resolve the Tissue Floater Conundrum.

Liron Pantanowitz^1,2, Pamela Michelow², Scott Hazelhurst³, Shivam Kalra^4,5, Charles Choi⁵, Sultaan Shah⁵, Morteza Babaie⁴, Hamid R Tizhoosh⁴

¹From the Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania (Pantanowitz).

²Department of Anatomical Pathology, University of the Witwatersrand and National Health Laboratory Services, Johannesburg, South Africa (Pantanowitz, Michelow).

³School of Electrical & Information Engineering and Sydney Brenner Institute for Molecular Bioscience, University of the Witwatersrand, Johannesburg, South Africa (Hazelhurst).

⁴Kimia Lab, University of Waterloo, Waterloo, Ontario, Canada (Kalra, Babaie, Tizhoosh).

⁵Huron Digital Pathology, Engineering Department, St. Jacobs, Ontario, Canada (Kalra, Choi, Shah). Pantanowitz is now with the Department of Pathology & Clinical Labs, University of Michigan, Ann Arbor.

PubMed DOI

Abstract

CONTEXT.—: Pathologists may encounter extraneous pieces of tissue (tissue floaters) on glass slides because of specimen cross-contamination. Troubleshooting this problem, including performing molecular tests for tissue identification if available, is time consuming and often does not satisfactorily resolve the problem. OBJECTIVE.—: To demonstrate the feasibility of using an image search tool to r…

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