Opto-acoustic imaging of relative blood oxygen saturation and total hemoglobin for breast cancer diagnosis.

Jason Zalev^1,2, Lisa M Richards¹, Bryan A Clingman¹, Jeff Harris¹, Edgar Cantu¹, Gisela L G Menezes¹, Carlos Avila¹, Allison Bertrand¹, Xavier Saenz¹, Steve Miller¹, Alexander A Oraevsky³, Michael C Kolios²

¹Seno Medical Instruments, Inc., San Antonio, Texas, United States.

²Ryerson University, Department of Physics, Toronto, Ontario, Canada.

³TomoWave Laboratories, Inc., Houston, Texas, United States.

PubMed PMC DOI PDF

Abstract

Opto-acoustic imaging involves using light to produce sound waves for visualizing blood in biological tissue. By using multiple optical wavelengths, diagnostic images of blood oxygen saturation and total hemoglobin are generated using endogenous optical contrast, without injection of any external contrast agent and without using any ionizing radiation. The technology has been used in recent clinic…

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