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Peer-Reviewed Publication
Mol Med Rep2019;20(2):1819-1825.August 1, 2019Journal Article

Characteristics of olfactory ensheathing cells and microarray analysis in Tupaia belangeri (Wagner, 1841).

Na Lin1, Xiu-Juan Dong2, Ting-Yong Wang1, Wen-Ji He3, Jing Wei4, Hai-Ying Wu5, Ting-Hua Wang1
1Institute of Neuroscience, Kunming Medical University, Kunming, Yunnan 650500, P.R. China.
2Department of Physical Education, Hainan Normal University, Haikou, Hainan 571100, P.R. China.
3Department of Ultrasonic Cardiogram, Kunming Children's Hospital, Kunming Medical University, Kunming, Yunnan 650228, P.R. China.
4Department of Pharmacy, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650000, P.R. China.
5Department of Emergency, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650000, P.R. China.

Abstract

Tree shrews are most closely related to the primates and so possess a number of advantages in experimental studies; they have been used as an animal model in bacterial and virus infection, cancer, endocrine system disease, and certain nervous system diseases. Their olfactory ensheathing cells (OECs) are able to release several cytokines to promote neuronal survival, regeneration and remyelination.…

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