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Peer-Reviewed Publication
Magn Reson Med2019;81(2):839-851.February 1, 2019Journal Article

A regional bolus tracking and real-time B1 calibration method for hyperpolarized 13 C MRI.

Shuyu Tang1, Eugene Milshteyn1, Galen Reed2, Jeremy Gordon3, Robert Bok3, Xucheng Zhu1, Zihan Zhu1, Daniel B Vigneron1, Peder E Z Larson1
1UC Berkeley-UCSF Graduate Program in Bioengineering, University of California, San Francisco and University of California, Berkeley, California.
2HeartVista, Los Altos, California.
3Department of Radiology and Biomedical Imaging, University of California-San Francisco, San Francisco, California.
PubMed PMC DOI PDF

Abstract

PURPOSE: Acquisition timing and B1 calibration are two key factors that affect the quality and accuracy of hyperpolarized 13 C MRI. The goal of this project was to develop a new approach using regional bolus tracking to trigger Bloch-Siegert B1 mapping and real-time B1 calibration based on regional B1 measurements, followed by dynamic imaging of hyperpolarized 13 C metabolites in vivo. METHODS: T…

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