Peer-Reviewed Publication
PLoS One2018;13(8):e0201469.January 1, 2018Evaluation Study

Patient-specific anatomical model for deep brain stimulation based on 7 Tesla MRI.

Yuval Duchin1,2, Reuben R Shamir2, Remi Patriat1, Jinyoung Kim2,3, Jerrold L Vitek4, Guillermo Sapiro3, Noam Harel1
1Center for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, MN, United States of America.
2Surgical Information Sciences, Minneapolis, MN, United States of America.
3Departments of Electrical & Computer Engineering, Computer Science, Biomedical Engineering and Math, Duke University, Durham, NC, United States of America.
4Department of Neurology, University of Minnesota, Minneapolis, MN, United States of America.

Abstract

OBJECTIVE: Deep brain stimulation (DBS) requires accurate localization of the anatomical target structure, and the precise placement of the DBS electrode within it. Ultra-high field 7 Tesla (T) MR images can be utilized to create patient-specific anatomical 3D models of the subthalamic nuclei (STN) to enhance pre-surgical DBS targeting as well as post-surgical visualization of the DBS lead positio…

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