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Peer-Reviewed Publication
Circ Cardiovasc Interv2017;10(9)September 1, 2017Journal Article

Validation Study of Image-Based Fractional Flow Reserve During Coronary Angiography.

Mariano Pellicano1, Ifat Lavi1, Bernard De Bruyne2, Hana Vaknin-Assa1, Abid Assali1, Orna Valtzer1, Yonit Lotringer1, Giora Weisz1, Yaron Almagor1, Panagiotis Xaplanteris1, Ajay J Kirtane1, Pablo Codner1, Martin B Leon1, Ran Kornowski1
1From the Cardiovascular Center Aalst, OLV Hospital, Belgium (M.P., B.D.B., P.X.); Rabin Medical Center, Petach Tikva, Israel (I.L., H.V.-A., A.A., O.V., P.C., R.K.); Department of Advanced Biomedical Sciences, Federico II University of Naples, Italy (M.P.); CathWorks Ltd, Ra'anana, Israel (I.L., O.V., Y.L.); Columbia University Medical Center, New York-Presbyterian Hospital (A.J.K., P.C., M.B.L.); and Shaare Zedek Medical Center, Jerusalem, Israel (G.W., Y.A.).
2From the Cardiovascular Center Aalst, OLV Hospital, Belgium (M.P., B.D.B., P.X.); Rabin Medical Center, Petach Tikva, Israel (I.L., H.V.-A., A.A., O.V., P.C., R.K.); Department of Advanced Biomedical Sciences, Federico II University of Naples, Italy (M.P.); CathWorks Ltd, Ra'anana, Israel (I.L., O.V., Y.L.); Columbia University Medical Center, New York-Presbyterian Hospital (A.J.K., P.C., M.B.L.); and Shaare Zedek Medical Center, Jerusalem, Israel (G.W., Y.A.). bernard.de.bruyne@olvz-aalst.be.

Abstract

BACKGROUND: Fractional flow reserve (FFR), an index of the hemodynamic severity of coronary stenoses, is derived from invasive measurements and requires a pressure-monitoring guidewire and hyperemic stimulus. Angiography-derived FFR measurements (FFRangio) may have several advantages. The aim of this study is to assess the diagnostic performance and interobserver reproducibility of FFRangio in pat…

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