In vitro antiviral activity against rotavirus and astrovirus infection exerted by substances obtained from Achyrocline bogotensis (Kunth) DC. (Compositae).

M A Téllez¹, A N Téllez², F Vélez³, J C Ulloa⁴

¹Laboratorio de Virología, Departamento de Microbiología, Facultad de Ciencias, Grupo de Enfermedades Infecciosas, Pontificia Universidad Javeriana, Cra. 7 # 43-82, Bogotá, Colombia.

²Laboratorio de Fitoquímica, Departamento de Química, Facultad de Ciencias, Grupo de Investigación en Fitoquímica, Pontificia Universidad Javeriana, Bogotá, Colombia.

³Departamento de Matemáticas, Grupo de Investigación Signos, Universidad El Bosque, Bogotá, Colombia.

⁴Laboratorio de Virología, Departamento de Microbiología, Facultad de Ciencias, Grupo de Enfermedades Infecciosas, Pontificia Universidad Javeriana, Cra. 7 # 43-82, Bogotá, Colombia. julloa@javeriana.edu.co.

PubMed PMC DOI PDF

Abstract

BACKGROUND: Achyrocline bogotensis has been traditionally used to treat infections of skin, respiratory, tract urinary and other infections, but not to treat viral gastrointestinal disease. In this study, this Colombian native medicinal plant was investigated by its in vitro anti-rotavirus and anti-astrovirus activity. METHODS: Several extracts and fractions phytochemically obtained from A. bogot…

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