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Peer-Reviewed Publication
Eur J Cancer2006;42(8):1083-92.May 1, 2006Comparative Study

Adverse effects to quality of life arising from treatment can recover with intermittent androgen suppression in men with prostate cancer.

N A Spry1, L Kristjanson, B Hooton, L Hayden, G Neerhut, H Gurney, T Corica, E Korbel, S Weinstein, K McCaul
1Department of Medicine, University of Western Australia, Perth, WA, Australia. Nigel.Spry@health.wa.gov.au

Abstract

Health-related quality of life (HQOL) research is a means of broadening the assessment of treatment effects. This longitudinal study investigated the dynamic change to quality of life (QOL) and testosterone dependant physiology in men commencing an intermittent maximal androgen blockade program (IMAB). Two hundred and fifty men were accrued to the multi-centre study of IMAB (Flutamide 250 mg TDS,…

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