Mahmood Lab

Mass General Brigham · Boston, MA, United States

Lab42 peopleRepresentation Learning for PathologyMultimodal Representation Learning and Generative AI

Lab profile

About Mahmood Lab

The lab develops machine learning, data fusion, and medical image analysis methods for objective diagnosis, prognosis, and biomarker discovery in computational pathology. They focus on developing automated mechanisms to reduce interobserver variability in cancer diagnosis using AI as an assistive tool for pathologists, and on identifying clinically relevant morphologic phenotypes and biomarkers associated with therapeutic response. The lab develops multimodal fusion algorithms combining information from multiple imaging modalities, patient histories, and multi-omics data for precise diagnostic, prognostic and therapeutic determinations.

Representation Learning for PathologyMultimodal Representation Learning and Generative AIWeakly Supervised Learning3D PathologyMultimodal Data FusionMultiplex ImagingAgentic AI for Diagnosis and Biomedical DiscoveryFoundation Models

01 · Research focus

Research areas and highlights

Topics and recent work as stated on the lab’s own site.

  • UNI - Towards a general-purpose foundation model for computational pathologyA general purpose foundation model for computational pathology trained on 100 million pathology images from over 100k WSIs and adapted to over 30 different downstream tasks.
  • PathChat - A Multimodal generative AI chatbot for pathologyA vision-language AI assistant for Pathology that can analyze histology images and answer diverse pathology-related queries.
  • CONCH - Vision-language foundation model for pathologyA vision-language foundation model for computational pathology trained on 1.17 million pathology image-text pairs and adapted to 14 different downstream tasks.
  • TriPath - Weakly Supervised AI for Efficient Analysis of 3D Pathology SamplesA method for weakly supervised AI for 3D pathology that enables 3D computational pathology via 3D multiple instance learning allowing AI models to capture intricate morphological details from pathology volumes.
  • TITAN - A multimodal whole slide foundation model for computational pathologyMultimodal whole slide foundation models published in Nature Medicine.

02 · People

Leadership and researchers

People listed on the lab’s team pages, by role.

Dongmin BangPostdoctoral Fellow
Kutsev BengisuPostdoctoral Fellow
Kutsev BingisuResearch Fellow, NIH
Iain CarmichaelPostdoctoral Fellow (Alumni)
Tiffany ChenPostdoctoral Fellow (Alumni)
Guillaume JaumePostdoctoral Fellow
Jana LipkovaPostdoctoral Fellow (Alumni)
Fabienne LucasAssistant Professor, University of Washington
Andrew SongPostdoctoral Fellow
Trinh VuongPostdoctoral Fellow
Drew FK WilliamsonAssistant Professor, Emory University
Drew WilliamsonPostdoctoral Fellow (Alumni)

03 · Research intelligence

Research Intelligence evidence

Publications, grants and clinical trials linked to the lab’s researchers in Health AI Central’s research data.

Research

Publications & preprints

All 10 since 2024 →
Funding

Active NIH grants

No active NIH grants; 1 earlier grant linked to this lab’s researchers.

All 1 →

04 · Updates

Updates and lab news

News and events from the lab’s own site.

No news has been collected from the lab’s site yet.

05 · Official presence

Lab sources and channels

The lab’s own pages and accounts.

06 · Related

Related labs and centers

Labs at the same institution and labs working on similar topics.