Feasibility & Site Selection
Network-driven site selection using real-time EHR data
Company profile
Company profile
Paradigm Health is transforming clinical trial execution through an AI-native platform that integrates directly with healthcare provider systems and workflows. The company addresses critical inefficiencies in drug development, where 50% of trials fail to meet enrollment targets and the average drug takes 12+ years to reach market at a cost exceeding $2.6 billion. Paradigm Health's end-to-end solution serves both trial sponsors and research sites, offering protocol optimization, feasibility analysis, site selection, patient identification, enrollment acceleration, and automated data capture. The platform leverages real-time EHR data and AI-powered screening to identify eligible patients within provider workflows, supported by experienced clinical research coordinators. For sponsors, Paradigm Health delivers faster study startup, stronger enrollment performance, and higher-quality data through eSource-powered sites and automated data workflows. For providers, the platform simplifies research conduct by reducing administrative burden and enabling seamless integration with existing care delivery. The company operates a network of over 100 research sites across the United States, Japan, and Israel, partnering with community healthcare providers and academic medical centers. Paradigm Health supports Phase I-IV clinical trials, including interventional, observational, and pragmatic studies, with particular strength in oncology and rare disease research. The company's approach has demonstrated measurable outcomes, including 6.5x faster enrollment in multiple myeloma trials and 45% increased enrollment at partner sites like Highlands Oncology.
Company description Paradigm official website
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01 · Operating footprint
Company-profile context for clinical focus, customers, deployment, integration, milestones, and partnerships.
Cloud Saas · Hybrid deployment with recorded integration context.
Recorded integration context: EDC systems, EHR systems, eSource connectivity.
Company milestones
Network expansion to 100+ research sites across US, Japan, and Israel; partnerships with 75% of top 20 biopharma sponsors; demonstrated 6.5x enrollment acceleration in multiple myeloma trials
Partnerships
02 · Flagship portfolio
Selected source-backed Company products and the available commercial context.
Network-driven site selection using real-time EHR data
AI-native clinical trial platform connecting sponsors, sites, and patients
AI-powered patient screening and enrollment within provider workflows
Full-service support for late-phase and post-approval research
Data-driven protocol design and feasibility modeling for clinical trials
Automated source data capture and EHR-to-EDC connectivity
03 · Research intelligence
Publications, preprints, clinical validation, and regulatory records in Evidence Position order.
Publications, clinical validation, and regulatory records connected to this Company appear here.
Research
Cancer letters · Aug 27, 2026
Decoding osteosarcoma mechanobiology: PIEZO channels in tumor progression, immune remodeling, and pain.Cancer metastasis reviews · Aug 19, 2026
Recalibrating sham-relative superiority thresholds in BPH device trials.World journal of urology · Aug 13, 2026
Childhood exposure to pornography and the normalization of online exploitation.Nursing · Aug 1, 2026
Selective portal vein occlusion and myocardial injury after major hepatobiliary surgery: a propensity-weighted cohort study.Scientific reports · Jul 20, 2026
Exposure to particulate matter induces health and developmental abnormalities in the Drosophila model.Scientific reports · Jul 7, 2026
Clinical validation
NCT06917404 · Sponsor · ACTIVE NOT RECRUITING
Efficacy and Safety Study to Evaluate SD-101 in Epidermolysis BullosaNCT07482787 · Sponsor · RECRUITING
Regulatory
No linked records are currently available.
04 · Company-reported outcomes
Company-reported outcomes and customer stories are distinct from linked Research Intelligence evidence.
Multiple Myeloma trial compared to traditional approaches
Multiple Myeloma trial enrollment costs
Highlands Oncology over two years
Altru Health System clinical trial participation
Optimize research portfolio and increase clinical trial enrollment
Increased clinical trial enrollment from 4% to 11%
Increase clinical trial patient enrollment while reducing research department burden
45% increase in clinical trial patient enrollment over two years
Accelerate enrollment for Multiple Myeloma clinical trial
6.5x faster enrollment, 20-30% cheaper compared to traditional approaches
Drive enrollment for ultra-rare disease basket trial
Over 10% of total trial enrollment driven by Paradigm Health, including first-patient-in on one rare, biomarker-defined trial arm
Identify high-volume sites with diverse patient populations for breast cancer trial
Identified 27 US community oncology sites with high volume of racially and ethnically diverse potentially eligible patients
05 · Leadership
Leadership profiles and professional links from the current Company record.
Adam Torres
Director of Research Development, Highlands Oncology
06 · Company updates
Recent articles published on Paradigm's official website.
07 · HAIC coverage
Health AI Central reporting that mentions this Company.
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Clinical AI · Jul 3, 2026
A groundbreaking UK study demonstrates that early intervention with an existing drug can prevent the onset of debilitating autoimmune disease in high-risk patients, opening the door for AI-powered predictive screening.
Clinical AI · Jul 3, 2026
Australian researchers have developed a soft robotic heart that uses artificial intelligence to replicate both healthy and diseased cardiac conditions, offering a breakthrough alternative for medical device testing.
Clinical AI · Jul 3, 2026
Mechanistic AI that explains *why* drugs work—rather than just predicting outcomes—could finally give regulators the transparency needed to accelerate drug development and reduce catastrophic trial failures.
Drug Discovery & Research · Jun 26, 2026
This internal sensing system continuously monitors heart rate, breathing, and metabolic states—and disruptions may explain why patients feel anxious or unwell without obvious cause.
Clinical AI · Jun 18, 2026
Cellular reprogramming uses Yamanaka factors to reset the epigenetic clock without erasing cell identity, with Life Biosciences now testing this aging reversal approach in human glaucoma patients for the first time.
Clinical AI · Jun 18, 2026
08 · Official presence
Curated official destinations from the active Company record.
09 · Market pathway
Other active Companies in the same market, selected alphabetically from the HAIC directory.
Market context
Companies using AI to optimize clinical trial design, accelerate patient recruitment, match patients to trials, predict trial outcomes, or improve clinical research efficiency. Includes patient enrollment and screening platforms, AI-powered trial matching, and tools that reduce the time and cost of bringing new treatments to market.
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Linked research, clinical, and regulatory source pathways.
Expanded product, deployment, integration, and partnership research.
Record-level provenance and review context.