OpenEvidence

OpenEvidence

Generative AI & Healthcare Infrastructure

About OpenEvidence

OpenEvidence is a medical AI platform that organizes and expands the world's collective medical knowledge for healthcare professionals. Founded on the principle of 'gold in, gold out,' the platform uses specialized AI models trained exclusively on peer-reviewed medical literature rather than the open internet, ensuring every answer is grounded in verifiable sources. The company has established official content partnerships with The New England Journal of Medicine (NEJM), JAMA and the JAMA Network, the National Comprehensive Cancer Network (NCCN), Cochrane Systematic Reviews, Wiley's portfolio of 400+ medical journals, and leading medical societies including ACC, ADA, AAFP, NORD, ACOG, AUA, AAO, and ACEP. As of 2025, OpenEvidence is actively used daily by over 40% of U.S. physicians across more than 10,000 hospitals and medical centers nationwide, with more than 25,000 verified U.S. doctors registering each month. The platform provides natural-language search capabilities that allow clinicians to access evidence-based recommendations, clinical guidelines, and peer-reviewed research at the point of care. OpenEvidence has expanded beyond search to include OpenEvidence Visits for clinical documentation and the AI-Integrated Doctor Dialer for HIPAA-secure telemedicine communications, messaging, faxing, and voicemail. The platform is free and unlimited for verified U.S. healthcare professionals and is available via web and mobile app.

Mission & Story

Mission

OpenEvidence's mission is to organize and expand the world's collective medical knowledge.

Founding Story

OpenEvidence was founded by Daniel Nadler, PhD, who built the platform on the principle of 'gold in, gold out' — using specialized AI models trained on peer-reviewed literature rather than the open internet, with every answer grounded in sources physicians can verify. The founding motivation addresses the problem that medical knowledge doubles every 73 days, yet it takes an average of 17 years for published research to reach clinical practice.

Clinical Focus

Medical conditions and clinical areas addressed by OpenEvidence.

oncologycardiologyendocrinologygeriatricshematologyinternal medicineneurologyobstetricspsychiatryrheumatologydermatologygastroenterology

Who It Serves

physicianshealthcare professionalshospitalsmedical centers

Milestones & Awards

Recent Milestones

February 2025: Multi-year content agreement with NEJM Group. November 2025: Licensing agreement with NCCN for oncology guidelines. March 2026: Strategic partnership with Wiley for 400+ journals including Cochrane. February 2026: Wide release of AI-Integrated Doctor Dialer with messaging, faxing, and voicemail capabilities.

Awards & Recognition

Described as fastest-growing clinical decision support platform in the United States. Noted as fastest platform in medical industry history to surpass 100,000 verified doctor users. Described as having adoption rate faster than any technology except the iPhone among doctors.

Key Partnerships

NEJM GroupJAMA and JAMA NetworkNational Comprehensive Cancer Network (NCCN)CochraneWileyAmerican College of Cardiology (ACC)American Diabetes Association (ADA)American Academy of Family Physicians (AAFP)National Organization for Rare Disorders (NORD)American College of Obstetricians and Gynecologists (ACOG)American Urological Association (AUA)American Academy of Ophthalmology (AAO)American College of Emergency Physicians (ACEP)Mayo Clinic

Social & Media

Company Details

Founded
2023
Headquarters
Miami, FL, USA

Work here?

Claim this listing to update company information and connect with our audience.

Claim This Listing

Security & Compliance

HIPAA
Last updated Jun 30, 2026

Similar Companies in this Market

View all 40
1upHealth

1upHealth

AI-powered health data platform that integrates and normalizes patient data from multiple sources to enable interoperability and clinical decision support across healthcare systems.

Aidbox

Aidbox

Health Samurai provides Aidbox, an enterprise FHIR server and backend platform that enables healthcare organizations to build solutions from clinical data repositories to EHRs. The platform offers PostgreSQL-based FHIR data management, multi-version FHIR support (STU3, R4, R5, R6), and comprehensive SDKs for rapid development.

Altera Digital Health

Altera Digital Health

Altera Digital Health provides comprehensive EHR and healthcare IT solutions for hospitals, health systems, and physician practices. The company offers acute, ambulatory, and financial platforms including Sunrise, Paragon, TouchWorks EHR, and CareInMotion interoperability solutions, alongside AI-powered tools for clinical documentation and revenue cycle management.

Amigo AI

Amigo AI

Amigo AI provides an enterprise platform for healthcare organizations to build, train, and deploy clinical AI agents that handle patient interactions across multiple specialties. The platform uses a rigorous 'Digital Residency' training approach with simulated patient scenarios to ensure clinical safety before deployment.

athenahealth

athenahealth

1001-5000 employees

athenahealth provides cloud-based healthcare technology solutions including EHR, revenue cycle management, and patient engagement tools. The company serves healthcare organizations of all sizes with an integrated platform designed to improve clinical and financial outcomes.

Atropos Health

Atropos Health

Atropos Health generates high-quality, personalized Real-World Evidence (RWE) in minutes using AI-powered automation. The company serves health systems, life sciences, and researchers with publication-grade observational studies to support clinical decisions, formulary management, and regulatory research.

Autonomize

Autonomize

Autonomize AI provides an AI-native intelligence platform that transforms fragmented healthcare operations into autonomous, intelligent workflows. The company deploys healthcare-specific AI agents and workflows across utilization management, care management, claims, pharmacy, and appeals for health systems and payers.

AvoMD

AvoMD

AvoMD provides EHR-integrated AI copilots that combine patient data with trusted medical guidelines to support clinical workflows. Their platform includes ambient documentation, chart assistance, AI consult tools, and intelligent pathways for hospitals and ambulatory care settings.

Data Accuracy Notice: Company information on HealthAI Central is compiled from public sources and updated regularly. While we strive for accuracy, details such as funding figures, employee counts, and product offerings may change. We recommend verifying critical information directly with the company before making business decisions.