Altera™
Comprehensive tumor genomic profiling test
Company profile
Company profile
Natera is a global leader in cell-free DNA (cfDNA) testing and molecular diagnostics, serving patients and clinicians across oncology, women's health, organ health, and rare disease. The company's mission is to advance molecular diagnostics with integrity and scientific rigor, supporting the integration of test information into healthcare decision-making to enable more personalized care. Natera's technology platform measures fetal, tumor, or donor cfDNA at the molecular level through noninvasive testing. In oncology, products include Signatera™ for residual disease monitoring (MRD), Latitude™ for tissue-free MRD, Altera™ for tumor genomic profiling, and Empower™ for hereditary cancer screening. In organ health, Prospera™ tests assess kidney, heart, and lung transplant rejection, while Renasight™ provides kidney gene panel testing. Women's health offerings include Horizon™ carrier screening, Panorama™ noninvasive prenatal testing (NIPT), Vistara™ single-gene NIPT, and Anora™ miscarriage testing. The rare disease portfolio features Zenith™ genomic testing. Natera's tests are clinically validated in over 400 peer-reviewed publications with over 3 million patients studied. The company has participated in major prospective studies including CIRCULATE (oncology), SMART (women's health), and Trifecta (organ health). With over 16 million tests processed in CAP/CLIA-certified laboratories and more than 150 medical professionals on staff, Natera delivers high-quality molecular diagnostic results that help clinicians make more informed treatment decisions and enable earlier, more targeted interventions.
Company description Natera official website
Claim this profile to manage Company information and connect with the Health AI Central audience.
01 · Operating footprint
Company-profile context for clinical focus, customers, deployment, integration, milestones, and partnerships.
Cloud Saas · On Premise · Other deployment with recorded integration context.
Recorded integration context: EHR Integration via Constellation Platform, NateraConnect Provider Portal, Oncology Portal, Organ Health Portal, ProReach, Rare Disease Portal, Women's Health Portal.
Company milestones
Signatera™ received regulatory approval in Japan for colorectal cancer (June 2024), strategic partnerships with Aveta Biomics and Eledon announced (June 2026), bladder cancer guideline update includes Signatera™-guided care, over 16 million tests processed
Partnerships
02 · Flagship portfolio
Selected source-backed Company products and the available commercial context.
Comprehensive tumor genomic profiling test
Genetic analysis for miscarriage tissue
Laboratory platform for implementing next-generation genomic testing
Hereditary cancer genetic testing
Advanced carrier screening for genetic conditions
Tissue-free MRD test for cancer monitoring
Provider portal for ordering tests and viewing results
Comprehensive support services for test implementation
AI-powered educational assistant for Empower test
03 · Research intelligence
Publications, preprints, clinical validation, and regulatory records in Evidence Position order.
Publications, clinical validation, and regulatory records connected to this Company appear here.
Research
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · Dec 1, 2026
Real-world analysis of ctDNA and other biomarkers in patients with curatively resected stage I-III biliary tract cancer.ESMO gastrointestinal oncology · Sep 1, 2026
Clinical significance of WES-defined ERBB2 amplification in resectable colorectal cancer.International journal of clinical oncology · Aug 20, 2026
Adapt or Become Irrelevant: the Pathologist as the new Diagnostic Architect.Journal of clinical pathology · Aug 17, 2026
Unified definition of integrated diagnostics: a position statement of the EFLM.Clinical chemistry and laboratory medicine · Aug 7, 2026
A straightforward framework to harmonize computational pathology.Journal of pathology informatics · Aug 1, 2026
Clinical validation
NCT05174169 · Sponsor · RECRUITING
Signatera-Guided CDK4/6 Inhibitor Therapy in Breast CancerNCT07214532 · Sponsor · RECRUITING
TPG: Tafasitamab, Polatuzumab Vedotin, and Glofitamab as First-line Therapy for Diffuse Large B-cell Lymphoma and High-grade B-cell LymphomaNCT07502872 · Sponsor · NOT YET RECRUITING
Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCLNCT06500273 · Sponsor · RECRUITING
ctDNA-Guided Therapy for Relapsed/Refractory Hodgkin LymphomaNCT07021989 · Sponsor · RECRUITING
ABCSG 61 / TEODOR : Neoadjuvant TrEatment Optimization Driven by Circulating Tumor DNA and endOcrine ResponsivenessNCT07084558 · Sponsor · RECRUITING
Regulatory
No linked records are currently available.
04 · Company-reported outcomes
Company-reported outcomes and customer stories are distinct from linked Research Intelligence evidence.
Oncology MRD testing with Signatera™
Transplant monitoring with Prospera™
Prenatal and carrier screening
Women's health testing for genetic condition screening
Implementation of Constellation platform for genomic testing
Organ health testing for transplant monitoring
Oncology testing for cancer monitoring
Implementation of Constellation platform for genomic testing
05 · Leadership
Leadership profiles and professional links from the current Company record.
No active leadership profiles are currently listed.
06 · Company updates
Recent articles published on Natera's official website.
No Company updates are currently listed.
07 · HAIC coverage
Health AI Central reporting that mentions this Company.
No HAIC coverage is currently linked to this Company.
08 · Official presence
Curated official destinations from the active Company record.
09 · Market pathway
Other active Companies in the same market, selected alphabetically from the HAIC directory.
Market context
Companies using AI to analyze genomic, proteomic, metabolomic, or multi-omics data to provide personalized treatment recommendations, identify genetic risks, or develop targeted therapies. Includes genomic sequencing platforms with AI analysis, preventive medicine based on genetic risk assessment, and longevity care based on molecular and genetic data.
Explore the full market directory or compare this Company with additional active profiles.
View all Companies in this market10 · Pro research
Expanded Company research is in development.
Health AI Central Pro · Coming Soon
Pro Research will introduce expanded technical context, linked evidence analysis, and comparative Company research.
Linked research, clinical, and regulatory source pathways.
Expanded product, deployment, integration, and partnership research.
Record-level provenance and review context.