Biospecimen Services
End-to-end biospecimen collection, processing, storage, and shipment for pre-clinical research
Service · ServiceCompany source
Company profile
About Circuit Clinical
Circuit Clinical is an Integrated Research Organization (IRO) on a mission to transform how people access and experience clinical trials. Founded in 2016 and headquartered in Buffalo, New York, the company brings clinical research directly to community healthcare settings rather than requiring patients to travel to traditional academic research centers. Circuit Clinical has built one of the largest IROs in the United States, providing direct EMR access to over 2.5 million participants within their partner health systems. The company operates through multiple Community Research Networks, including a Growing Site Partnership Network embedded in communities and a Remote Site Network of Principal Investigators across the US. Their approach enables physicians to conduct clinical research in-office, online, or through hybrid models, with dedicated medical, legal, and regulatory staff handling backend operations. Circuit Clinical serves three primary constituencies: patients seeking clinical trials as a care option, physicians wanting to conduct research, and industry sponsors/CROs needing recruitment and enrollment support. Circuit Clinical's solutions include traditional on-site Phase I-IV clinical trial management, biospecimen collection and processing services, and MD PreScreen—a proprietary screening service led by experienced research nurses. The company has completed over 300 clinical projects and works with 150+ Principal Investigators across 20+ physician groups in eight geographic regions. Their strategic partnerships include Medidata (creating turnkey DCT solutions), Labcorp (expanding access through FQHCs), and NextGen Healthcare (leveraging comprehensive data for diverse trial recruitment). Circuit Clinical is committed to democratizing clinical trials and improving representation in medical research.
Company description Circuit Clinical official website
Primary marketClinical Trials & Research
Commercial modelCommercial information available on request
Company presenceOfficial website
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01 · Operating footprint
Where the Company operates
Company-profile context for clinical focus, customers, deployment, integration, milestones, and partnerships.
Clinical focus
- Breast cancer
- Cardiovascular disease
- Colorectal cancer
- Oncology
- Respiratory diseases (RSV)
- Various Phase I-IV conditions
Who it serves
- Community healthcare providers
- CROs
- FQHCs
- Health systems
- Pharmaceutical sponsors
- Physician groups
Deployment & integration
Cloud Saas · Hybrid · On Premise · Service deployment with recorded integration context.
Recorded integration context: EMR systems, Medidata Rave, Medidata TrialJourney, myMedidata, NextGen Healthcare.
Geographic context
MarketsHudson New York · Northern New Jersey · Philadelphia · South Central Kentucky · United States · Western New York
Company sourceOfficial website
Company milestones
Platform expansion
Partnership with Western New York Medical (July 2025); Partnership with Mercer Allergy & Pulmonary Associates (August 2024); SSM Health partnership for oncology trials (January 2024); Graves Gilbert partnership in Kentucky (September 2023); Terminated merger agreement with Lightship Inc. (July 2025); Moderna mResvia RSV vaccine approval involvement (June 2024)
Partnerships
Recorded partners
- Crystal Run Healthcare
- Graves Gilbert
- Impact Medical
- IZ Medical
- Labcorp
- Medidata
- Mercer Allergy & Pulmonary Associates
- Middletown Medical
- NextGen Healthcare
- Niagara Falls Memorial Medical Center
- North Hudson Community Action Corporation
- Orchard Park Family Practice
- Pottstown Medical Specialists
- Riverside Medical Group
- SSM Health
- Western New York Medical
02 · Flagship portfolio
Products, workflows, and platform capabilities
Selected source-backed Company products and the available commercial context.
Clinical Services
Traditional on-site Phase I-IV clinical trial management for diverse populations
Service · On PremiseCompany source
MD Prescreen
Expert screening service optimizing clinical trial participant lead generation
Service · ServiceCompany source
Remote Site Network
Always-ready network of Principal Investigators conducting decentralized clinical trials across the US
Platform · Cloud SaaSCompany source
Site Partnership Network
Community-embedded clinical trial sites bringing research to underrepresented populations
Platform · HybridCompany source
TrialScout
Patient-facing platform for clinical trial awareness and engagement
Platform · Cloud SaaSCompany source
03 · Research intelligence
Research Intelligence evidence
Publications, preprints, clinical validation, and regulatory records in Evidence Position order.
Evidence position
Publications, clinical validation, and regulatory records connected to this Company appear here.
Research
Publications & preprints
Impact of the CAPTURE Chronic Obstructive Pulmonary Disease Screening Tool in U.S. Primary Care: A Cluster-Randomized Trial.American journal of respiratory and critical care medicine · May 1, 2025
Discriminative Accuracy of the CAPTURE Tool for Identifying Chronic Obstructive Pulmonary Disease in US Primary Care Settings.JAMA · Feb 14, 2023
Clinical validation
Clinical-trial records
A Study of Lebrikizumab (LY3650150) in Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP)NCT06338995 · Mentioned · RECRUITING
A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung CancerNCT06119581 · Mentioned · RECRUITING
A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)NCT06717347 · Mentioned · RECRUITING
Post Market Registry for the Omnipod 5 System in Children and Adults With Type 1 DiabetesNCT06144554 · Mentioned · RECRUITING
A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)NCT06430801 · Mentioned · RECRUITING
A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)NCT07060807 · Mentioned · RECRUITING
Regulatory
Regulatory records
No linked records are currently available.
04 · Company-reported outcomes
Outcomes and case studies
Company-reported outcomes and customer stories are distinct from linked Research Intelligence evidence.
2.5 million participants
Direct EMR access within partner health systems
300+ clinical projects
Completed clinical trials
150+ Principal Investigators
In network
20+ physician groups
In partnership network
8 geographic regions
Coverage across US
SSM Health
Partnership to expand access to leading-edge oncology trials through clinical research
Expanded oncology trial access in community healthcare settings
Graves Gilbert
Partnership with Circuit Clinical and Labcorp to bring clinical trials to patients across South Central Kentucky
Brought clinical trial access to previously underserved South Central Kentucky region
Medidata
Created industry's first turnkey DCT solution by integrating Rave, TrialJourney, and myMedidata to expand access and elevate patient experience
Created unified decentralized clinical trial experience through strategic partnership
Labcorp
Partnership to create fully functional clinical trial sites in communities through Labcorp's network of providers, physicians, and FQHCs
Expanded access to clinical trials in underrepresented communities through FQHC network
NextGen Healthcare
Combined NextGen's comprehensive data and national reach with Circuit's patient-centric recruitment services
Groundbreaking opportunities for accelerating therapeutic development and improving diversity in clinical trials
05 · Leadership
Leadership team
Leadership profiles and professional links from the current Company record.
Irfan Khan
CEO & Founder
Kerry Hicks
Executive Chairman
Susanne Oltz
Chief Financial Officer
Margaret Scott
Senior Vice President, Clinical Operations
Laura Warwick
Senior Vice President, Commercial
Kathy Bean
Vice President, Technology & Clinical Informatics
06 · Company updates
Updates from Circuit Clinical
Recent articles published on Circuit Clinical's official website.
07 · HAIC coverage
Coverage and analysis
Health AI Central reporting that mentions this Company.
No HAIC coverage is currently linked to this Company.
08 · Official presence
Company sources and channels
Curated official destinations from the active Company record.
09 · Market pathway
Additional Companies in this Market
Other active Companies in the same market, selected alphabetically from the HAIC directory.
Market context
Clinical Trials & Research
Companies using AI to optimize clinical trial design, accelerate patient recruitment, match patients to trials, predict trial outcomes, or improve clinical research efficiency. Includes patient enrollment and screening platforms, AI-powered trial matching, and tools that reduce the time and cost of bringing new treatments to market.
Explore the full market directory or compare this Company with additional active profiles.
View all Companies in this market
10 · Pro research
Coming soon
Expanded Company research is in development.
Health AI Central Pro · Coming Soon
Deeper Company research is coming soon.
Pro Research will introduce expanded technical context, linked evidence analysis, and comparative Company research.
Linked research, clinical, and regulatory source pathways.
Expanded product, deployment, integration, and partnership research.
Record-level provenance and review context.