About Circuit Clinical
Circuit Clinical is an Integrated Research Organization (IRO) on a mission to transform how people access and experience clinical trials. Founded in 2016 and headquartered in Buffalo, New York, the company brings clinical research directly to community healthcare settings rather than requiring patients to travel to traditional academic research centers. Circuit Clinical has built one of the largest IROs in the United States, providing direct EMR access to over 2.5 million participants within their partner health systems. The company operates through multiple Community Research Networks, including a Growing Site Partnership Network embedded in communities and a Remote Site Network of Principal Investigators across the US. Their approach enables physicians to conduct clinical research in-office, online, or through hybrid models, with dedicated medical, legal, and regulatory staff handling backend operations. Circuit Clinical serves three primary constituencies: patients seeking clinical trials as a care option, physicians wanting to conduct research, and industry sponsors/CROs needing recruitment and enrollment support. Circuit Clinical's solutions include traditional on-site Phase I-IV clinical trial management, biospecimen collection and processing services, and MD PreScreen—a proprietary screening service led by experienced research nurses. The company has completed over 300 clinical projects and works with 150+ Principal Investigators across 20+ physician groups in eight geographic regions. Their strategic partnerships include Medidata (creating turnkey DCT solutions), Labcorp (expanding access through FQHCs), and NextGen Healthcare (leveraging comprehensive data for diverse trial recruitment). Circuit Clinical is committed to democratizing clinical trials and improving representation in medical research.
Mission & Story
Mission
Circuit Clinical is on a mission that matters. We're bringing clinical trials to physicians and the diverse patient populations they serve, not the other way around. We're developing a physician-focused, patient-centric process that will revolutionize how people engage with their healthcare.
Founding Story
Circuit Clinical was founded in 2016 by Irfan Khan, MD. The company was born from a vision to transform clinical trial access by bringing research into community healthcare settings rather than limiting it to academic research centers in larger cities. In 2020, the Board named Irfan Khan, MD, as CEO and Kerry Hicks (formerly of Healthgrades) as Executive Chairman. The company won the 43North competition, a startup investment incubator located in Buffalo, NY, which helped accelerate its growth.
Clinical Focus
Medical conditions and clinical areas addressed by Circuit Clinical.
Who It Serves
Milestones & Awards
Recent Milestones
Partnership with Western New York Medical (July 2025); Partnership with Mercer Allergy & Pulmonary Associates (August 2024); SSM Health partnership for oncology trials (January 2024); Graves Gilbert partnership in Kentucky (September 2023); Terminated merger agreement with Lightship Inc. (July 2025); Moderna mResvia RSV vaccine approval involvement (June 2024)
Awards & Recognition
Inc Magazine Best Workplaces (2022); Fast Company #20 Nationally Best Workplaces for Innovators (2022); Fast Company World Changing Ideas (2022); 43North competition winner (2020); TrialScout named 1st runner-up at DPHARM (2020)
Key Partnerships
Social & Media
Company Details
- Founded
- 2016
- Headquarters
- Buffalo, NY, USA
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