Company profile

Cardio-Phoenix

Cardiology & Cardiovascular Health

Company profile

About Cardio-Phoenix

Cardio-Phoenix has developed Cardio-HART, a clinically validated AI-powered cardiac diagnostic system that transforms point-of-care cardiac assessment in primary care. The system builds on standard 12-lead ECG functionality by adding structural and functional cardiac insights traditionally only available through echocardiography in secondary care settings. Cardio-HART uses synchronized electrical, acoustic, and mechanical biosignal sensing combined with AI models to detect electrical abnormalities, structural heart disease, valvular pathology (aortic stenosis, mitral regurgitation), and all three heart failure phenotypes (HFpEF, HFmrEF, HFrEF) during a single 10-minute examination. The system provides quantified left ventricular ejection fraction (LVEF) with severity grading, achieving over 90% agreement with echocardiographic measurements. Validated across 15,000+ patients in 14 European centers, Cardio-HART demonstrates 91.2% sensitivity and 88.6% specificity for heart failure detection, reduces inconclusive ECG results by 94%, and increases confirmed diagnoses by 160% compared to standard ECG alone. The technology enables general practitioners and primary care clinicians to make more confident referral decisions, reducing unnecessary echocardiography referrals by up to 66% while identifying high-priority patients who require specialist assessment. Cardio-HART functions as both a triage and diagnostic support tool, bridging the diagnostic gap between ECG screening and echocardiography, ultimately enabling earlier clinical decision-making before symptoms escalate.

Company description Cardio-Phoenix official website

Primary marketCardiology & Cardiovascular Health
Commercial modelCommercial information available on request
Company presenceLinkedIn X
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01 · Operating footprint

Where the Company operates

Company-profile context for clinical focus, customers, deployment, integration, milestones, and partnerships.

Clinical focus

  • Aortic stenosis
  • Cardiomyopathies
  • ECG abnormalities (rhythm, conduction, ischemia)
  • Heart failure (HFpEF, HFmrEF, HFrEF)
  • Mitral regurgitation
  • Structural heart disease
  • Valvular heart disease

Who it serves

  • Cardiologists
  • General Practitioners
  • Healthcare Commissioners
  • Heart Failure Pathway Teams
  • Primary Care Clinics

Deployment & integration

On Premise deployment with recorded integration context.

Geographic context

MarketsEuropean Union (14 centers) · Spain · United Kingdom
Company sourceOfficial website

Company milestones

Platform expansion

Real-world nurse-led screening pilot in Spain (2025) with 47 tests in 5 hours detecting 3 early-HF cases. Multi-center post-market study completed (2023) with 15,000+ patients. Clinical validation published in European Heart Journal - Digital Health (2024).

Partnerships

Recorded partners

  • Royal Society of Medicine (endorsement from President Dr Teresa Castiello)

02 · Flagship portfolio

Products, workflows, and platform capabilities

Selected source-backed Company products and the available commercial context.

Cardio-HART

AI-powered cardiac diagnostic system delivering echo-level insights at ECG speed in primary care

Device · On PremiseCompany source

03 · Research intelligence

Research Intelligence evidence

Publications, preprints, clinical validation, and regulatory records in Evidence Position order.

Evidence position

Publications, clinical validation, and regulatory records connected to this Company appear here.

Research

Publications & preprints

No linked records are currently available.

Clinical validation

Clinical-trial records

No linked records are currently available.

Regulatory

Regulatory records

Cardio-TriTest v6.5

K182790 · 510k · Dec 14, 2018

04 · Company-reported outcomes

Outcomes and case studies

Company-reported outcomes and customer stories are distinct from linked Research Intelligence evidence.

94% reduction in inconclusive ECGs

31% to 1.9% inconclusive rate vs standard ECG

160% increase in confirmed diagnoses

10% to 26% diagnostic yield in primary care

91.2% sensitivity / 88.6% specificity for heart failure detection

All HF phenotypes combined

96% agreement with Simpson Biplane LVEF

Correlation r=0.78, RMSE ≈8%

Up to 66% reduction in echo referrals

Through improved point-of-care triage

>90% positive predictive value for heart failure

Compared to 50% false-positive rate for NT-proBNP

≥97% negative predictive value

Multi-disease screening

Diagnósticos F.C. Community Screening (Spain)

Nurse-led community cardiac screening for early heart failure detection

47 tests completed in 5 hours with 10-minute turnaround; detected 3 asymptomatic heart failure cases

Multi-centre European Study (14 sites)

Clinical validation of AI-powered cardiac diagnostics across diverse patient populations

96% agreement with echocardiography; 94% reduction in inconclusive ECGs (31% to 1.9%); 160% increase in confirmed GP diagnoses (10% to 26%)

NHS (UK Health System)

Primary care heart failure pathway optimization and reduction of unnecessary echocardiography referrals

35-40% reduction in unnecessary echocardiography referrals

Dr Teresa Castiello Practice

Replacement of standard ECG with Cardio-HART for improved cardiac diagnostics in cardiology practice

High diagnostic confidence with echo confirmation of Cardio-HART findings; potential to reduce unnecessary echos and accelerate patient answers at NHS scale

05 · Leadership

Leadership team

Leadership profiles and professional links from the current Company record.

Dr Teresa Castiello

Clinical Advisor (Cardiology President of Royal Society of Medicine)

06 · Company updates

Updates from Cardio-Phoenix

Recent articles published on Cardio-Phoenix's official website.

07 · HAIC coverage

Coverage and analysis

Health AI Central reporting that mentions this Company.

No HAIC coverage is currently linked to this Company.

08 · Official presence

Company sources and channels

Curated official destinations from the active Company record.

09 · Market pathway

Additional Companies in this Market

Other active Companies in the same market, selected alphabetically from the HAIC directory.

Market context

Cardiology & Cardiovascular Health

Companies applying AI to cardiovascular disease detection, ECG/EKG analysis, heart failure management, cardiac imaging, arrhythmia detection, or cardiovascular risk assessment. Includes AI-powered cardiac diagnostics, non-invasive hemodynamic monitoring, and tools for early detection and personalized management of heart conditions.

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10 · Pro research

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Expanded Company research is in development.

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Deeper Company research is coming soon.

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ResearchEvidence analysis

Linked research, clinical, and regulatory source pathways.

CompanyTechnical context

Expanded product, deployment, integration, and partnership research.

MethodSource & review record

Record-level provenance and review context.

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