Company profile

AiCure

Clinical Trials & Research

Company profile

About AiCure

AiCure is a leading AI and advanced data analytics company specializing in clinical trial optimization through its flagship platform, H.Code. The company has pioneered AI-powered adherence verification technology trusted by pharmaceutical companies, contract research organizations (CROs), and healthcare providers to verify medication and clinical behavior adherence across the healthcare lifecycle. H.Code combines AI-powered computer vision, synchronous chat, and predictive analytics to remotely observe and assist trial participants through their smartphones, revolutionizing access and participation while improving statistical power and deepening understanding of the relationship between patient behavior and trial outcomes. The platform supports all types of clinical trials—traditional site-based, decentralized, fully virtual, or hybrid models—across any therapeutic indication. AiCure's technology has been deployed across more than 2,200 clinical trial sites in 46 countries, capturing over 1.5 million participant doses with a 92% participant retention rate. The company's research demonstrates that early medication adherence captured through H.Code can serve as a marker for participant retention, with their Clinical Site Services framework reducing early termination rates for adherent participants to just 7.8% across 28 phase I-IV clinical trials. AiCure serves seven of the top 10 global pharmaceutical companies and has been awarded 84 patents for its innovative approach to clinical trial patient engagement and adherence monitoring.

Company description AiCure official website

Primary marketClinical Trials & Research
Commercial modelCommercial information available on request
Company presenceOfficial website
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01 · Operating footprint

Where the Company operates

Company-profile context for clinical focus, customers, deployment, integration, milestones, and partnerships.

Clinical focus

  • Alzheimer's disease
  • Autism
  • Depression
  • Hepatitis C
  • HIV
  • Neurodegenerative diseases
  • Parkinson's disease
  • Schizophrenia

Who it serves

  • Clinical trial sites
  • Contract Research Organizations (CROs)
  • Healthcare providers
  • Pharmaceutical companies

Deployment & integration

Cloud Saas · Hybrid deployment with recorded integration context.

Recorded integration context: Additional patient data sources, Clinical workflows and records, Patient companion apps.

Geographic context

Markets46 countries · Global deployment
Company sourceOfficial website

Company milestones

Platform expansion

Over 2,200 clinical trial sites deployed, 1.5+ million participant doses captured, 84 patents awarded, research published on early termination prediction

Partnerships

Recorded partners

  • 7 of top 10 global pharmaceutical companies
  • Abbvie
  • Cerevel Therapeutics
  • Sage Therapeutics

02 · Flagship portfolio

Products, workflows, and platform capabilities

Selected source-backed Company products and the available commercial context.

AiCurator

Clinical site dashboards for trial monitoring and participant management

Software · Cloud SaaSCompany source

Clinical Site Services (CSS)

Tech-enabled operational monitoring framework to reduce early termination

Service · HybridCompany source

Digital Phenotypes

Audio and visual digital biomarker detection for treatment response monitoring

Software · Cloud SaaSCompany source

H.Code

AI-powered adherence verification platform for clinical trials and healthcare

Platform · Cloud SaaSCompany source

Patient Connect

Mobile app for real-time medication adherence and remote patient monitoring

Software · Cloud SaaSCompany source

03 · Research intelligence

Research Intelligence evidence

Publications, preprints, clinical validation, and regulatory records in Evidence Position order.

Evidence position

Publications, clinical validation, and regulatory records connected to this Company appear here.

Research

Publications & preprints

AI-based medication adherence prediction in patients with schizophrenia and attenuated psychotic disorders.

Schizophrenia research · Jan 1, 2025

Acceptability of an automated directly observed therapy (DOT) application for PrEP adherence support among young men who have sex with men: a qualitative exploration.

AIDS care · Nov 1, 2024

Identifying Unmet Needs in Major Depressive Disorder Using a Computer-Assisted Alternative to Conventional Thematic Analysis: Qualitative Interview Study With Psychiatrists.

JMIR formative research · Mar 1, 2024

Randomized Controlled Trial of Automated Directly Observed Therapy for Measurement and Support of PrEP Adherence Among Young Men Who have Sex with Men.

AIDS and behavior · Feb 1, 2023

Opportunities for digital health technology: identifying unmet needs for bipolar misdiagnosis and depression care management.

Frontiers in digital health · Jan 1, 2023

Characterizing clinical pediatric obesity subtypes using electronic health record data.

PLOS digital health · Aug 1, 2022

Clinical validation

Clinical-trial records

DOT Diary Mobile App for Pre-Exposure Prophylaxis Adherence in Young Men

NCT03771638 · Sponsor · COMPLETED

Youth Ending the HIV Epidemic

NCT05789875 · Sponsor · COMPLETED

DOT Diary Optimization Pilot: A Pilot Study to Optimize the DOT Diary App to Measure PrEP Adherence

NCT03387462 · Sponsor · COMPLETED

Smartphone Based aDOT Treatment With Fixed-Dose Elbasvir and Grazoprevir in PWIDs

NCT03127358 · Sponsor · COMPLETED

Using Artificial Intelligence To Monitor Medication Adherence in Opioid Replacement Therapy

NCT02243670 · Sponsor · COMPLETED

Using Artificial Intelligence to Measure and Optimize Adherence in Patients on Anticoagulation Therapy.

NCT02599259 · Sponsor · COMPLETED

Regulatory

Regulatory records

No linked records are currently available.

04 · Company-reported outcomes

Outcomes and case studies

Company-reported outcomes and customer stories are distinct from linked Research Intelligence evidence.

92% participant retention rate

Across clinical trials using H.Code platform

1.5+ million participant doses captured

Total doses verified through platform

7.8% early termination rate

For adherent participants across 28 phase I-IV trials with 4,000+ patients

50%+ reduction in dropout rates

Reported by Abbvie - dropout rates cut by more than half

Abbvie

Reducing participant dropout rates in clinical trials

Drop-out rates cut down by more than half

Cerevel Therapeutics

Advanced facial recognition and mapping for detecting subtle clinical changes

Most advanced in facial recognition and mapping software for clinical detection

Multiple Pharma Companies

Reducing early termination in clinical trials through tech-enabled monitoring

Early termination rates reduced to 7.8% for adherent participants across 28 phase I-IV trials with 4,000+ patients in 43 countries

Sage Therapeutics

Using AiCure as an active data collection tool to drive clinical action

Shifted from passive data collection to action-driving tool

05 · Leadership

Leadership team

Leadership profiles and professional links from the current Company record.

Matthew Leoni

VP, Global Clinical Development

LinkedIn

Sarah Titus

Director of Clinical Operations & Development

Kyle Holen

Head of Development Design Center

06 · Company updates

Updates from AiCure

Recent articles published on AiCure's official website.

07 · HAIC coverage

Coverage and analysis

Health AI Central reporting that mentions this Company.

No HAIC coverage is currently linked to this Company.

08 · Official presence

Company sources and channels

Curated official destinations from the active Company record.

09 · Market pathway

Additional Companies in this Market

Other active Companies in the same market, selected alphabetically from the HAIC directory.

Market context

Clinical Trials & Research

Companies using AI to optimize clinical trial design, accelerate patient recruitment, match patients to trials, predict trial outcomes, or improve clinical research efficiency. Includes patient enrollment and screening platforms, AI-powered trial matching, and tools that reduce the time and cost of bringing new treatments to market.

Explore the full market directory or compare this Company with additional active profiles.

View all Companies in this market

10 · Pro research

Coming soon

Expanded Company research is in development.

Health AI Central Pro · Coming Soon

Deeper Company research is coming soon.

Pro Research will introduce expanded technical context, linked evidence analysis, and comparative Company research.

ResearchEvidence analysis

Linked research, clinical, and regulatory source pathways.

CompanyTechnical context

Expanded product, deployment, integration, and partnership research.

MethodSource & review record

Record-level provenance and review context.

Coming Soon