Peer-Reviewed Publication
Drug Alcohol Depend2026;288113379.September 26, 2026Journal Article

Medication for opioid use disorder following urine drug testing: An observational cohort study of linked national laboratory and medical and pharmacy claims data.

Bradley White1, Jonathan Skinner2, Tracy Hammonds3, Partha Bhattacharyya4, Mir M Ali5
1Division of Behavioral and Social Research, National Institute on Aging, National Institutes of Health, 31 Center Dr, Bethesda, MD 20892, United States. Electronic address: brad.white@nih.gov.
2Division of Behavioral and Social Research, National Institute on Aging, National Institutes of Health, 31 Center Dr, Bethesda, MD 20892, United States; National Bureau of Economic Research, 1050 Massachusetts Ave, Cambridge, MA 02138, United States. Electronic address: jonathan.skinner@dartmouth.edu.
3HealthVerity, Inc, 1818 Market Street, Suite 700, Philadelphia PA 19103, United States.. Electronic address: thammonds@healthverity.com.
4Division of Behavioral and Social Research, National Institute on Aging, National Institutes of Health, 31 Center Dr, Bethesda, MD 20892, United States; Office of the Chief Information Officer, US Department of Health and Human Services, 200 Independence Ave SW, Washington, DC 20201, United States. Electronic address: partha.bhattacharyya@hhs.gov.
5Division of Behavioral and Social Research, National Institute on Aging, National Institutes of Health, 31 Center Dr, Bethesda, MD 20892, United States; Office of the Chief Information Officer, US Department of Health and Human Services, 200 Independence Ave SW, Washington, DC 20201, United States. Electronic address: mir.ali@hhs.gov.

Abstract

BACKGROUND AND AIMS: Urine drug testing (UDT) is commonly used in opioid use disorder (OUD) care to assess substance use and inform clinical decision-making, yet little is known about how opioid UDT results are associated with subsequent medication for opioid (MOUD) use and adherence. This study examines the association between opioid UDT, post-UDT MOUD use, and treatment adherence using linked na…

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