Peer-Reviewed Publication
BMC Genomics2026;27(1)October 9, 2026Journal Article

ERMA: a harmonizing epicPCR data analysis tool.

Adrian Dörr1, Svjetlana Dekić Rozman2, Lina Viktoria Duncker1, Jan Kehrmann3, Jan Buer3, Marko Virta2, Folker Meyer1, Ivana Kraiselburd4
1Data Science Research Group, Institute for Artificial Intelligence in Medicine (IKIM), University Hospital of Essen, University of Duisburg-Essen, Essen, Germany.
2Institute of Microbiology, University of Helsinki, Helsinki, Finland.
3Institute for Medical Microbiology, University Hospital Essen, Essen, Germany.
4Data Science Research Group, Institute for Artificial Intelligence in Medicine (IKIM), University Hospital of Essen, University of Duisburg-Essen, Essen, Germany. ivana.kraiselburd@uk-essen.de.

Abstract

BACKGROUND: EpicPCR links functional genes to taxonomic markers at the single-cell level and has become an important method in microbial ecology and antimicrobial resistance research. However, the lack of missing standardized data analysis workflows limits reproducibility and comparability across studies. Existing analyses are often based on custom, unpublished scripts, complicating cross-study be…

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