TRIDENT: inTRaoperative Imaging DEvice based on endogeNous opTical properties to evaluate bowel oxygenation in left-sided colorectal resections. Observational first-in-human pilot safety trial.

Alfonso Lapergola^1,2, Luca Baratelli³, Gabriel Szydlo Shein⁴, Guillaume Philouze¹, Sylvain Kpekou³, Arturo Pardo³, Frédéric Triponez^5,6, Didier Mutter^1,2, Sylvain Gioux³, Michele Diana^7,8,9

¹Department of General, Digestive, and Endocrine Surgery, University Hospital of Strasbourg, Strasbourg, France.

²IHU-Strasbourg, Institute of Image-Guided Surgery, Strasbourg, France.

³Intuitive Surgical, Aubonne, Switzerland.

⁴ICube Laboratory, Photonics Instrumentation for Health, Strasbourg, France.

⁵Department of Surgery, University Hospital of Geneva, Geneva, Switzerland.

⁶Medical Faculty, University of Geneva, Geneva, Switzerland.

⁷ICube Laboratory, Photonics Instrumentation for Health, Strasbourg, France. michele.diana@unige.ch.

⁸Department of Surgery, University Hospital of Geneva, Geneva, Switzerland. michele.diana@unige.ch.

⁹Medical Faculty, University of Geneva, Geneva, Switzerland. michele.diana@unige.ch.

PubMed DOI

Abstract

BACKGROUND: Adequate tissue oxygenation at the anastomotic site is a key determinant of healing after colorectal surgery. Current intraoperative imaging technologies aimed at assessing bowel perfusion present several limitations, including the need for exogenous contrast agents, limited quantification capabilities, or suboptimal integration within the surgical workflow. Single Snapshot Imaging of…

Create a free account to keep reading

Free members get 10 full research views every month across publications, clinical trials, FDA clearances, adverse events, and NIH grants. No credit card required.

Create Free Account Sign In

Want unlimited research access? See Pro plans

Data Accuracy Notice: Research intelligence on Health AI Central is aggregated from public sources (PubMed, ClinicalTrials.gov, FDA, NIH, CMS, and others) and refreshed nightly. Classifications and derived metrics are produced by automated methods described in our Methodology. We recommend verifying critical data points against the primary sources before making decisions.