Health AI Central
Peer-Reviewed Publication
Cancer Res Commun2026October 12, 2026Journal Article

Elucidating the Gene Expression Signature of Rosai-Dorfman Disease: A Study from the Atlas of Blood Cancer Genomes Initiative.

Sheren Younes1, Fadzai Chinyengetere2, Veronica Russell2, Devang Thakkar3, Emily F Mason4, Ridas Juskevicius4, Alexandra E Kovach5, Shaoying Li6, C Cameron Yin6, Dennis P O'Malley7, Jean L Koff8, David L Jaye9, Cassandra Love10, Jennifer R Shingleton10, Dennis Owusu11, Ayush Batra11, Leonardo P A Biral2, Elizabeth Thacker3, Clay Parker3, Lanie Happ3, Jennifer Chapman Fredricks12, Izidore S Lossos13, Sarah L Ondrejka14, Eric Hsi15, Eric Tse16, Rex K H Au-Yeung17, Govind Bhagat18, Rebecca J Leeman-Neill19, Amy Chadburn20, Magdalena Czader21, Yuri Fedoriw22, Kikkeri N Naresh23, Sandeep S Dave10, Yasodha Natkunam24
1Stanford University Stanford, CA United States.
2Duke University Durham United States.
3Data Driven Bioscience United States.
4Vanderbilt University Medical Center Nashville, TN United States.
5Children's Hospital of Los Angeles Los Angeles, California United States.
6The University of Texas MD Anderson Cancer Center Houston, Texas United States.
7NeoGenomics (United States) United States.
8Emory University Atlanta United States.
9Emory University Atlanta, GA United States.
10Duke University Durham, NC United States.
11Duke University United States.
12University of Miami United States.
13University of Miami Miami, FL United States.
14Cleveland Clinic Cleveland, OH United States.
15Mayo Clinic Rochester, MN United States.
16University of Hong Kong Hong Kong Hong Kong.
17University of Hong Kong Pok Fu Lam, HK Island Hong Kong.
18Saint Louis University Saint Louis, Missouri United States.
19Columbia University New York, NY United States.
20Weill Cornell Medicine New York, NY United States.
21Indiana University School of Medicine Indianapolis, IN United States.
22University of North Carolina at Chapel Hill Chapel Hill, NC United States.
23Fred Hutch Cancer Center Seattle, Washington United States.
24Stanford University Stanford, California United States.
PubMed DOI

Abstract

Rosai-Dorfman disease (RDD) is a rare histiocytic disorder characterized by accumulation of large histiocytes in nodal and/or extranodal sites. The underlying biology of RDD and factors that distinguish it from the other histiocyte disorders are poorly understood. To better understand the disease biology, we employed whole transcriptome RNA sequencing to study the gene expression profiles of RDD a…

Create a free account to keep reading

Free members get 10 full research views every month across publications, clinical trials, FDA clearances, adverse events, and NIH grants. No credit card required.

Create Free AccountSign In

Want unlimited research access? See Pro plans

Data Accuracy Notice: Research intelligence on Health AI Central is aggregated from public sources (PubMed, ClinicalTrials.gov, FDA, NIH, CMS, and others) and refreshed nightly. Classifications and derived metrics are produced by automated methods described in our Methodology. We recommend verifying critical data points against the primary sources before making decisions.